An emerging role for epigenetic dysregulation in arsenic toxicity and carcinogenesis
Background Exposure to arsenic, an established human carcinogen, through consumption
of highly contaminated drinking water is a worldwide public health concern. Several …
of highly contaminated drinking water is a worldwide public health concern. Several …
[HTML][HTML] Chronic arsenic toxicity: studies in West Bengal, India
DG Mazumder, UB Dasgupta - The Kaohsiung journal of medical sciences, 2011 - Elsevier
Chronic arsenic toxicity (arsenicosis) as a result of drinking arsenic-contaminated
groundwater is a major environmental health hazard throughout the world, including India. A …
groundwater is a major environmental health hazard throughout the world, including India. A …
Molecular mechanisms of arsenic-induced disruption of DNA repair
Exposure to arsenic in contaminated drinking water is an emerging public health problem
that impacts more than 200 million people worldwide. Accumulating lines of evidence from …
that impacts more than 200 million people worldwide. Accumulating lines of evidence from …
Liver and adipose expression associated SNPs are enriched for association to type 2 diabetes
Genome-wide association studies (GWAS) have demonstrated the ability to identify the
strongest causal common variants in complex human diseases. However, to date, the …
strongest causal common variants in complex human diseases. However, to date, the …
Effects of arsenic exposure on DNA methylation in cord blood samples from newborn babies and in a human lymphoblast cell line
P Intarasunanont, P Navasumrit, S Waraprasit… - Environmental …, 2012 - Springer
Background Accumulating evidence indicates that in utero exposure to arsenic is associated
with congenital defects and long-term disease consequences including cancers. Recent …
with congenital defects and long-term disease consequences including cancers. Recent …
Epigenetic remodeling during arsenical-induced malignant transformation
TJ Jensen, P Novak, KE Eblin, AJ Gandolfi… - …, 2008 - academic.oup.com
Humans are exposed to arsenicals through many routes with the most common being in
drinking water. Exposure to arsenic has been associated with an increase in the incidence …
drinking water. Exposure to arsenic has been associated with an increase in the incidence …
Chronic low-level arsenic exposure causes gender-specific alterations in locomotor activity, dopaminergic systems, and thioredoxin expression in mice
U Bardullas, JH Limón-Pacheco, M Giordano… - Toxicology and Applied …, 2009 - Elsevier
Arsenic (As) is a toxic metalloid widely present in the environment. Human exposure to As
has been associated with the development of skin and internal organ cancers and …
has been associated with the development of skin and internal organ cancers and …
Toxicogenomics of arsenic: classical ideas and recent advances
Exposure to arsenic, a toxic metalloid distributed widely in nature, has been known to result
in hazardous health outcomes including cancer. Incidence of arsenic toxicity, mostly from …
in hazardous health outcomes including cancer. Incidence of arsenic toxicity, mostly from …
Arsenic exposure induces genomic hypermethylation
S Majumdar, S Chanda, B Ganguli… - Environmental …, 2010 - Wiley Online Library
Gene‐specific hypermethylation has previously been detected in Arsenic exposed persons.
To monitor the level of whole genome methylation in persons exposed to different levels of …
To monitor the level of whole genome methylation in persons exposed to different levels of …
Epigenetic mediated transcriptional activation of WNT5A participates in arsenical-associated malignant transformation
TJ Jensen, RJ Wozniak, KE Eblin, SM Wnek… - Toxicology and applied …, 2009 - Elsevier
Arsenic is a human carcinogen with exposure associated with cancer of the lung, skin, and
bladder. Many potential mechanisms have been implicated as playing a role in the process …
bladder. Many potential mechanisms have been implicated as playing a role in the process …