Chagas' disease

C Bern - New England Journal of Medicine, 2015 - Mass Medical Soc
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Overview and recent advances in the treatment of neuroblastoma

SB Whittle, V Smith, E Doherty, S Zhao… - Expert review of …, 2017 - Taylor & Francis
Introduction: Children with neuroblastoma have widely divergent outcomes, ranging from
cure in> 90% of patients with low risk disease to< 50% for those with high risk disease …

[HTML][HTML] Experimental and clinical treatment of Chagas disease: a review

PAS Junior, I Molina, SMF Murta… - The American journal …, 2017 - ncbi.nlm.nih.gov
Chagas disease (CD) is caused by the protozoan parasite Trypanosoma cruzi that infects a
broad range of triatomines and mammalian species, including man. It afflicts 8 million …

Proteasome inhibition for treatment of leishmaniasis, Chagas disease and sleeping sickness

S Khare, AS Nagle, A Biggart, YH Lai, F Liang… - Nature, 2016 - nature.com
Chagas disease, leishmaniasis and sleeping sickness affect 20 million people worldwide
and lead to more than 50,000 deaths annually. The diseases are caused by infection with …

Randomized trial of posaconazole and benznidazole for chronic Chagas' disease

I Molina, J Gómez i Prat, F Salvador… - … England Journal of …, 2014 - Mass Medical Soc
Background Current therapeutic options for Chagas' disease are limited to benznidazole
and nifurtimox, which have been associated with low cure rates in the chronic stage of the …

Prevalence of Chagas disease in Latin-American migrants living in Europe: a systematic review and meta-analysis

A Requena-Méndez, E Aldasoro… - PLoS neglected …, 2015 - journals.plos.org
Background Few studies have assessed the burden of Chagas disease in non-endemic
countries and most of them are based on prevalence estimates from Latin American (LA) …

Chagas disease: an overview of clinical and epidemiological aspects

MCP Nunes, W Dones, CA Morillo, JJ Encina… - Journal of the American …, 2013 - jacc.org
Chagas disease, caused by the parasite Trypanosoma cruzi, is a serious health problem in
Latin America and is an emerging disease in non-endemic countries. In recent decades, the …

Diagnosis and management of Chagas disease and cardiomyopathy

AL Ribeiro, MP Nunes, MM Teixeira… - Nature Reviews …, 2012 - nature.com
Chagas cardiomyopathy is the most severe and life-threatening manifestation of human
Chagas disease—a'neglected'tropical disease caused by the protozoan parasite …

3ª diretriz brasileira de transplante cardíaco

F Bacal, FG Marcondes-Braga, LEP Rohde… - Arquivos brasileiros de …, 2018 - SciELO Brasil
Prezados colegas, Grandes avanços no diagnóstico, monitorização e tratamento da
Insuficiência Cardíaca (IC) foram observados nos últimos anos, com impactos reais na …

Bioluminescence imaging of chronic Trypanosoma cruzi infections reveals tissue‐specific parasite dynamics and heart disease in the absence of locally persistent …

MD Lewis, A Fortes Francisco, MC Taylor… - Cellular …, 2014 - Wiley Online Library
Chronic T rypanosoma cruzi infections lead to cardiomyopathy in 20–30% of cases. A
causal link between cardiac infection and pathology has been difficult to establish because …