[HTML][HTML] Endothelial dysfunction: is there a hyperglycemia-induced imbalance of NOX and NOS?

CA Meza, JD La Favor, DH Kim… - International journal of …, 2019 - mdpi.com
NADPH oxidases (NOX) are enzyme complexes that have received much attention as key
molecules in the development of vascular dysfunction. NOX have the primary function of …

Exercise is the real polypill

C Fiuza-Luces, N Garatachea, NA Berger… - Physiology, 2013 - journals.physiology.org
The concept of a “polypill” is receiving growing attention to prevent cardiovascular disease.
Yet similar if not overall higher benefits are achievable with regular exercise, a drug-free …

Wearable/disposable sweat-based glucose monitoring device with multistage transdermal drug delivery module

H Lee, C Song, YS Hong, M Kim, HR Cho, T Kang… - Science …, 2017 - science.org
Electrochemical analysis of sweat using soft bioelectronics on human skin provides a new
route for noninvasive glucose monitoring without painful blood collection. However, sweat …

[HTML][HTML] Discovery of drug–omics associations in type 2 diabetes with generative deep-learning models

RL Allesøe, AT Lundgaard, R Hernández Medina… - Nature …, 2023 - nature.com
The application of multiple omics technologies in biomedical cohorts has the potential to
reveal patient-level disease characteristics and individualized response to treatment …

[HTML][HTML] Therapeutic host-directed strategies to improve outcome in tuberculosis

C Young, G Walzl, N Du Plessis - Mucosal immunology, 2020 - Elsevier
Abstract Bacille Calmette-Guérin (BCG) is the only licenced tuberculosis (TB) vaccine, but
has limited efficacy against pulmonary TB disease development and modest protection …

[HTML][HTML] Pharmacologic management of type 2 diabetes mellitus: available therapies

J Thrasher - The American journal of cardiology, 2017 - Elsevier
Choices for the treatment of type 2 diabetes mellitus (T2DM) have multiplied as our
understanding of the underlying pathophysiologic defects has evolved. Treatment should …

Resistance exercise versus aerobic exercise for type 2 diabetes: a systematic review and meta-analysis

Z Yang, CA Scott, C Mao, J Tang, AJ Farmer - Sports medicine, 2014 - Springer
Background Resistance and aerobic exercises are both recommended as effective
treatments for people with type 2 diabetes. However, the optimum type of exercise for the …

[HTML][HTML] Reappraisal of metformin efficacy in the treatment of type 2 diabetes: a meta-analysis of randomised controlled trials

R Boussageon, I Supper, T Bejan-Angoulvant… - PLoS …, 2012 - journals.plos.org
Background The UK Prospective Diabetes Study showed that metformin decreases mortality
compared to diet alone in overweight patients with type 2 diabetes mellitus. Since then, it …

Antihyperglycemic effects of short term resveratrol supplementation in type 2 diabetic patients

A Movahed, I Nabipour, X Lieben Louis… - Evidence‐Based …, 2013 - Wiley Online Library
The objective of this study was to examine the effectiveness of resveratrol in lowering blood
glucose in the presence of standard antidiabetic treatment in patients with type 2 diabetes, in …

[HTML][HTML] Prescribing exercise interventions for patients with chronic conditions

TC Hoffmann, CG Maher, T Briffa, C Sherrington… - Cmaj, 2016 - Can Med Assoc
Mortality benefits from exercise are similar to pharmacologic interventions for secondary
prevention of coronary heart disease, stroke rehabilitation, treatment for heart failure and …