[HTML][HTML] Endothelial dysfunction: is there a hyperglycemia-induced imbalance of NOX and NOS?
NADPH oxidases (NOX) are enzyme complexes that have received much attention as key
molecules in the development of vascular dysfunction. NOX have the primary function of …
molecules in the development of vascular dysfunction. NOX have the primary function of …
Exercise is the real polypill
C Fiuza-Luces, N Garatachea, NA Berger… - Physiology, 2013 - journals.physiology.org
The concept of a “polypill” is receiving growing attention to prevent cardiovascular disease.
Yet similar if not overall higher benefits are achievable with regular exercise, a drug-free …
Yet similar if not overall higher benefits are achievable with regular exercise, a drug-free …
Wearable/disposable sweat-based glucose monitoring device with multistage transdermal drug delivery module
Electrochemical analysis of sweat using soft bioelectronics on human skin provides a new
route for noninvasive glucose monitoring without painful blood collection. However, sweat …
route for noninvasive glucose monitoring without painful blood collection. However, sweat …
[HTML][HTML] Discovery of drug–omics associations in type 2 diabetes with generative deep-learning models
RL Allesøe, AT Lundgaard, R Hernández Medina… - Nature …, 2023 - nature.com
The application of multiple omics technologies in biomedical cohorts has the potential to
reveal patient-level disease characteristics and individualized response to treatment …
reveal patient-level disease characteristics and individualized response to treatment …
[HTML][HTML] Therapeutic host-directed strategies to improve outcome in tuberculosis
Abstract Bacille Calmette-Guérin (BCG) is the only licenced tuberculosis (TB) vaccine, but
has limited efficacy against pulmonary TB disease development and modest protection …
has limited efficacy against pulmonary TB disease development and modest protection …
[HTML][HTML] Pharmacologic management of type 2 diabetes mellitus: available therapies
J Thrasher - The American journal of cardiology, 2017 - Elsevier
Choices for the treatment of type 2 diabetes mellitus (T2DM) have multiplied as our
understanding of the underlying pathophysiologic defects has evolved. Treatment should …
understanding of the underlying pathophysiologic defects has evolved. Treatment should …
Resistance exercise versus aerobic exercise for type 2 diabetes: a systematic review and meta-analysis
Background Resistance and aerobic exercises are both recommended as effective
treatments for people with type 2 diabetes. However, the optimum type of exercise for the …
treatments for people with type 2 diabetes. However, the optimum type of exercise for the …
[HTML][HTML] Reappraisal of metformin efficacy in the treatment of type 2 diabetes: a meta-analysis of randomised controlled trials
R Boussageon, I Supper, T Bejan-Angoulvant… - PLoS …, 2012 - journals.plos.org
Background The UK Prospective Diabetes Study showed that metformin decreases mortality
compared to diet alone in overweight patients with type 2 diabetes mellitus. Since then, it …
compared to diet alone in overweight patients with type 2 diabetes mellitus. Since then, it …
Antihyperglycemic effects of short term resveratrol supplementation in type 2 diabetic patients
A Movahed, I Nabipour, X Lieben Louis… - Evidence‐Based …, 2013 - Wiley Online Library
The objective of this study was to examine the effectiveness of resveratrol in lowering blood
glucose in the presence of standard antidiabetic treatment in patients with type 2 diabetes, in …
glucose in the presence of standard antidiabetic treatment in patients with type 2 diabetes, in …
[HTML][HTML] Prescribing exercise interventions for patients with chronic conditions
Mortality benefits from exercise are similar to pharmacologic interventions for secondary
prevention of coronary heart disease, stroke rehabilitation, treatment for heart failure and …
prevention of coronary heart disease, stroke rehabilitation, treatment for heart failure and …