Mitochondria play a vital role in the nervous system, as they are responsible for generating
energy in the form of ATP and regulating cellular processes such as calcium (Ca 2+) …

Metabolic syndrome (MS) is a growing disorder affecting thousands of people worldwide,
especially in industrialised countries, increasing mortality. Oxidative stress, hyperglycaemia …

Oxidative stress plays a crucial role in the pathogenesis of hepatic encephalopathy (HE), but
the mechanism remains unclear. GABAergic neurons in substantia nigra pars reticulata …

Oxidative stress (OS) and inflammation are two important and well-studied pathological
hallmarks of neurodegenerative diseases (NDDs). Due to elevated oxygen consumption, the …

Mitochondria are one of the organelles undergoing rapid alteration during the senescence
process. Senescent cells show an increase in mitochondrial size, which is attributed to the …

Alzheimer's disease (AD) is a progressive neurodegenerative disorder that comprises
amyloid-beta protein (Aβ) as a main component of neuritic plaques. Its deposition is …

Sepsis is the most common cause of death from infection in the world. Unfortunately, there is
no specific treatment for patients with sepsis, and management relies on infection control …

Abstract MitoTEMPO (MT) and Visomitin (SKQ1) are regareded as mitochondria-targeted
antioxidants, which inhibit production of mitochondrial reactive oxygen species (ROS) …

Neurodegenerative diseases are emerging as a global health concern in the current
scenario, and their association with mitochondrial defects has been a potential area of …

Alzheimer's disease (AD) is the most common neurodegenerative disorder and the main
cause of dementia which is characterized by a progressive cognitive decline that severely …