Obesity and heart failure with preserved ejection fraction (HFpEF) represent two
intermingling epidemics driving perhaps the greatest unmet health problem in …

The prevalence of obesity-related glomerulopathy is increasing in parallel with the
worldwide obesity epidemic. Glomerular hypertrophy and adaptive focal segmental …

Global consumption of high‐fat diets (HFD) is associated with an increased incidence of
cardiometabolic syndrome and cardiac injury, warranting identification of cardioprotective …

Mesenchymal stem/stromal cells (MSCs) have distinct capability for renal repair, but may
have safety concerns. MSC-derived extracellular vesicles emerged as a novel noncellular …

The global increase in chronic kidney disease (CKD) parallels the obesity epidemic. Obesity
conveys a gradual but independent risk of progression of CKD that seems irrespective of the …

To diminish the learning curve associated with using swine as models, Swine in the
Laboratory: Surgery, Anesthesia, Imaging, and Experimental Techniques, Second Edition …

It is increasingly recognized that obesity is a risk factor for microvascular disease, involving
both structural and functional changes in the microvasculature. This review aims to describe …

Glomerular hyperfiltration is a characteristic functional abnormality in insulin-dependent
diabetes mellitus and occurs in the large majority of young Type 1 diabetic patients …

The metabolic syndrome (MetS) is a cluster of cardiovascular risk factors including insulin
resistance (IR), dyslipidemia, and hypertension, which may also foster development of …

A healthy adipose tissue (AT) is indispensable to human wellbeing. Among other roles, it
contributes to energy homeostasis and provides insulation for internal organs. Adipocytes …