Machine learning is increasingly integrated into clinical practice, with applications ranging
from pre-clinical data processing, bedside diagnosis assistance, patient stratification …

Trillions of commensal microbes live in our body, the majority in the gut. This gut microbiota
is in constant interaction with the homeostatic systems, the nervous, immune and endocrine …

Aging of the vasculature, which is integral to the functioning of literally all human organs,
serves as a fundamental physiological basis for age-related alterations as well as a shared …

Colitis is generally affected by multiple factors, including the dysbiosis of intestinal
microbiota, and may affect organs outside colon through circulation. Pectin, which is an …

Emerging evidence links dietary fiber with altered gut microbiota composition and bile acid
signaling in maintaining metabolic health. Yeast β-glucan (Y-BG) is a dietary supplement …

The treatment of PML/RARA+ acute promyelocytic leukemia (APL) with all-trans-retinoic acid
and arsenic trioxide (ATRA/ATO) has been recognized as a model for translational medicine …

We propose a novel machine-learning-based scoring function for drug discovery that
incorporates ligand and protein structural information into a knowledge-based PMF score …

Alzheimer's disease (AD) is a progressive and fatal neurodegenerative disease caused by a
combination of genetic and environmental risk factors. The serum metabolome refers to a set …

A group of disorders known as cardiovascular diseases (CVDs) affect the blood vessels that
supply the heart muscle. CVDs are the leading global cause of death; however, the absence …

This study describes the influence of Lactobacillus plantarum CCFM8610 on the host by
employing transcriptome and untargeted metabolomics. According to the enrichment …