Background Brentuximab vedotin (BV) is an antibody-drug conjucate (ADC) comprising a
CD30-directed antibody, conjugated to the microtubule-disrupting agent MMAE via a …

Anaplastic large cell lymphoma (ALCL) is the most common type of mature T-cell non-
Hodgkin lymphoma in children/adolescents. ALCL is characterized by expression of CD30 …

Objectives: To summarize the impact of relapsed/refractory primary cutaneous T-cell
lymphomas (CTCL) on quality of life (QoL) and the efficacy of available treatments in two …

Context.—Although CD30 testing is an established tool in the diagnostic workup of
lymphomas, it is also emerging as a predictive biomarker that informs treatment. The current …

Previously obscured within other designations of aggressive lymphomas, peripheral T-cell
lymphoma (PTCL) now represents 23 different subtypes of non-Hodgkin lymphoma (NHL) …

Although mycosis fungoides (MF) is characterized by an indolent course of disease (disease-
specific 5-year survival rate of up to 88%), disease progression or death occurs in nearly …

Introduction: Sézary syndrome (SS) is characterized by rapidly progressive disease and
poor survival. Although there is no standard treatment for SS, allogeneic stem cell …

Primary Objectives:• To evaluate the safety and tolerability of the combination of nivolumab
and brentuximab in subjects with the diagnosis of relapsed, refractory DLBCL, PTCL (all …

Chłoniaki pierwotnie skórne są heterogenną grupą nowotworów układu chłonnego, które
wywodzą się najczęściej z dojrzałych limfocytów T, rzadziej z dojrzałych limfocytów B i …