[HTML][HTML] Gastro-retentive drug delivery systems and their in vivo success: A recent update

UK Mandal, B Chatterjee, FG Senjoti - asian journal of pharmaceutical …, 2016 - Elsevier
Gastro-retentive drug delivery system (GRDDS) has gained immense popularity in the field
of oral drug delivery recently. It is a widely employed approach to retain the dosage form in …

Metronidazole Based Floating Bioadhesive Drug Delivery System for Potential Eradication of H. pylori: Preparation and In Vitro Characterization

F Naseem, SU Shah, SA Rashid, A Farid… - Polymers, 2022 - mdpi.com
Metronidazole has the potential to produce local stomach specific action in order to treat
Helicobacter pylori induced peptic ulcer disease. The current project executes the …

Gastro retentive drug delivery system: A review

S Ahmad, V Singh, SK Kushwaha - 2023 - indianjournals.com
Gastro Retentive Drug Delivery Systems (GRDDs) are an approach to prolonging gastric
residence time by targeting the release of specific drugs at the top of the GIT for local or …

Preparation and characterization of patch loaded with clarithromycin nanovesicles for transdermal drug delivery

A Zaid Alkilani, B Musleh, R Hamed… - Journal of Functional …, 2023 - mdpi.com
Clarithromycin (CLR), categorized as a Biopharmaceutical Classification System class II
drug, has several gastrointestinal tract side effects and an extremely unpalatable bitter taste …

Bioadhesive behaviors of HPMC E5: comparative analysis of various techniques, histological and human radiological evidence

OY Mady, O Dewedar, N Abdine, H Zaytoon… - Scientific Reports, 2024 - nature.com
Enhancing drug residence duration within the stomach offers distinct advantages for both
localized and systemic effects. Numerous strategies have been proposed to extend drug …

Preparation of high-drug-loaded clarithromycin gastric-floating sustained-release tablets using 3D printing

P Chen, H Luo, S Huang, J Liu, M Lin, F Yang… - AAPS …, 2021 - Springer
The high-drug-loaded sustained-release gastric-floating clarithromycin (CAM) tablets were
proposed and manufactured via semisolid extrusion (SSE)-based 3D printing. The physical …

Development of genipin-crosslinked fucoidan/chitosan-N-arginine nanogels for preventing Helicobacter infection

YH Lin, KY Lu, CL Tseng, JY Wu, CH Chen, FL Mi - Nanomedicine, 2017 - Taylor & Francis
Aim: This study aims to validate the anti-Helicobacter pylori efficacy of amoxicillin-loaded
nanoparticles and nanogels with pH-responsive and site-specific drug release properties …

Development and Characterization of PCL Electrospun Membrane-Coated Bletilla striata Polysaccharide-Based Gastroretentive Drug Delivery System

Z Li, R Zeng, L Yang, X Ren, KG Maffucci, Y Qu - Aaps Pharmscitech, 2020 - Springer
The purpose of this study was to investigate the potential of Bletilla striata polysaccharide
(BSP, a natural glucomannan material) for the development of a gastroretentive drug …

Preparation of clarithromycin floating core-shell systems (CSS) using multi-nozzle semi-solid extrusion-based 3D printing

P Chen, J Liu, K Zhang, D Huang, S Huang… - International journal of …, 2021 - Elsevier
Matrix erosion is unavoidable during the release of poorly soluble drugs from gastric floating
delivery system (GFDDS), which shortens the floating time and diminishes drug release. We …

Plant exine capsules based encapsulation strategy: a high loading and long-term effective delivery system for nobiletin

D Wu, Y Liang, Y Pei, B Li, H Liang - Food Research International, 2020 - Elsevier
The properties of high loading capacity and long-term absorption are of great significance in
the field of nutraceuticals or drugs delivery. Herein, we developed an innovative method to …