Neurotrophic keratopathy

HS Dua, DG Said, EM Messmer, M Rolando… - Progress in retinal and …, 2018 - Elsevier
Neurotrophic Keratopathy (NK) refers to a condition where corneal epitheliopathy leading to
frank epithelial defect with or without stromal ulceration (melting) is associated with reduced …

Corneal nerves in health and disease

MA Al-Aqaba, VK Dhillon, I Mohammed… - Progress in retinal and …, 2019 - Elsevier
The cornea is the most sensitive structure in the human body. Corneal nerves adapt to
maintain transparency and contribute to corneal health by mediating tear secretion and …

Current and emerging therapies for corneal neovascularization

D Roshandel, M Eslani, A Baradaran-Rafii… - The ocular …, 2018 - Elsevier
The cornea is unique because of its complete avascularity. Corneal neovascularization
(CNV) can result from a variety of etiologies including contact lens wear; corneal infections; …

Decellularization and recellularization of cornea: Progress towards a donor alternative

J Fernández-Pérez, M Ahearne - Methods, 2020 - Elsevier
The global shortage of donor corneas for transplantation has led to corneal bioengineering
being investigated as a method to generate transplantable tissues. Decellularized corneas …

Construction of tissue-engineered full-thickness cornea substitute using limbal epithelial cell-like and corneal endothelial cell-like cells derived from human embryonic …

C Zhang, L Du, P Sun, L Shen, J Zhu, K Pang, X Wu - Biomaterials, 2017 - Elsevier
The aim of this study was to construct a full-thickness artificial cornea substitute in vitro by
coculturing limbal epithelial cell-like (LEC-like) cells and corneal endothelial cell-like (CEC …

Lipid keratopathy: a review of pathophysiology, differential diagnosis, and management

MGN Hall, M Moshirfar, A Amin-Javaheri… - Ophthalmology and …, 2020 - Springer
Lipid keratopathy is a disease in which fat deposits accumulate in the cornea, leading to
opacification and decrease of visual acuity. This condition can be idiopathic without signs of …

Gene-based antiangiogenic applications for corneal neovascularization

S Liu, V Romano, B Steger, SB Kaye, KJ Hamill… - Survey of …, 2018 - Elsevier
Corneal avascularity is maintained by angiogenic privilege, an active process involving the
production of higher level of angiostatic factors to offset the effect of angiogenic factors. A …

Effects of climate factors and Demodex infestation on meibomian gland dysfunction-associated dry eye diseases

X Deng, W Qi, S Zhao, R Yang, C Zhang, Y Huang - Scientific Reports, 2024 - nature.com
We examined the effects of climatic factors and Demodex infestations on meibomian gland
dysfunction (MGD)-associated dry eye disease (DED) in a cross-sectional study. This study …

Evaluation of the ocular surface characteristics and Demodex infestation in paediatric and adult blepharokeratoconjunctivitis

M Wu, X Wang, J Han, T Shao, Y Wang - BMC ophthalmology, 2019 - Springer
Background To evaluate the ocular surface characteristics and the infestation of Demodex in
Chinese paediatric and adult blepharokeratoconjunctivitis (BKC). Methods Fifty consecutive …

Imaging of vascular abnormalities in ocular surface disease

V Romano, B Steger, M Ahmad, G Coco… - Survey of …, 2022 - Elsevier
The vascular system of the ocular surface plays a central role in infectious, autoimmune,
inflammatory, traumatic and neoplastic diseases. The development, application, and …