Physical exercise as an epigenetic modulator of brain plasticity and cognition

J Fernandes, RM Arida, F Gomez-Pinilla - Neuroscience & Biobehavioral …, 2017 - Elsevier
A large amount of evidence has demonstrated the power of exercise to support cognitive
function, the effects of which can last for considerable time. An emerging line of scientific …

[HTML][HTML] The impact of aerobic and resistance training intensity on markers of neuroplasticity in health and disease

T Hortobágyi, T Vetrovsky, GM Balbim… - Ageing Research …, 2022 - Elsevier
Objective To determine the effects of low-vs. high-intensity aerobic and resistance training
on motor and cognitive function, brain activation, brain structure, and neurochemical …

Rethinking concepts and categories for understanding the neurodevelopmental effects of childhood adversity

KE Smith, SD Pollak - Perspectives on psychological science, 2021 - journals.sagepub.com
Discovering the processes through which early adverse experiences affect children's
nervous-system development, health, and behavior is critically important for developing …

Physical exercise prevented stress‐induced anxiety via improving brain RNA methylation

L Yan, J Wei, F Yang, M Wang, S Wang… - Advanced …, 2022 - Wiley Online Library
Physical exercise is effective in alleviating mental disorders by improving synaptic
transmission; however, the link between body endurance training and neural adaptation has …

The Biology of Stress Intolerance in Patients with Chronic Pain—State of the Art and Future Directions

A Wyns, J Hendrix, A Lahousse, E De Bruyne… - Journal of clinical …, 2023 - mdpi.com
Stress has been consistently linked to negative impacts on physical and mental health. More
specifically, patients with chronic pain experience stress intolerance, which is an …

Impact of physical activity and exercise on the epigenome in skeletal muscle and effects on systemic metabolism

J Plaza-Diaz, D Izquierdo, Á Torres-Martos, AT Baig… - Biomedicines, 2022 - mdpi.com
Exercise and physical activity induces physiological responses in organisms, and
adaptations in skeletal muscle, which is beneficial for maintaining health and preventing …

Differential DNA methylation in experienced meditators after an intensive day of mindfulness-based practice: Implications for immune-related pathways

R Chaix, M Fagny, M Cosin-Tomás… - Brain, behavior, and …, 2020 - Elsevier
The human methylome is dynamically influenced by psychological stress. However, its
responsiveness to stress management remains underexplored. Meditation practice has …

Anaplastic lymphoma kinase in human cancer

A Barreca, E Lasorsa, L Riera… - Journal of …, 2011 - jme.bioscientifica.com
Although genetics determines endocrine phenotypes, it cannot fully explain the great
variability and reversibility of the system in response to environmental changes. Evidence …

Childhood adversity and epigenetic regulation of glucocorticoid signaling genes: Associations in children and adults

AR Tyrka, KK Ridout, SH Parade - Development and …, 2016 - cambridge.org
Early childhood experiences have lasting effects on development, including the risk for
psychiatric disorders. Research examining the biologic underpinnings of these associations …

Etiology matters–genomic DNA methylation patterns in three rat models of acquired epilepsy

KJ Dębski, A Pitkanen, N Puhakka, AM Bot, I Khurana… - Scientific reports, 2016 - nature.com
This study tested the hypothesis that acquired epileptogenesis is accompanied by DNA
methylation changes independent of etiology. We investigated DNA methylation and gene …