Modulated electro-hyperthermia-induced tumor damage mechanisms revealed in cancer models
The benefits of high-fever range hyperthermia have been utilized in medicine from the
Ancient Greek culture to the present day. Amplitude-modulated electro-hyperthermia …
Ancient Greek culture to the present day. Amplitude-modulated electro-hyperthermia …
The effects of localized heat on the hallmarks of cancer
G Hannon, FL Tansi, I Hilger… - Advanced …, 2021 - Wiley Online Library
Heat has been used to treat tumors for thousands of years. There are reports of the
Egyptians and Greek philosophers using such treatments as far back as 3000 BC and 500 …
Egyptians and Greek philosophers using such treatments as far back as 3000 BC and 500 …
Forcing the antitumor effects of HSPs using a modulated electric field
CA Minnaar, A Szasz - Cells, 2022 - mdpi.com
The role of Heat Shock Proteins (HSPs) is a “double-edged sword” with regards to tumors.
The location and interactions of HSPs determine their pro-or antitumor activity. The present …
The location and interactions of HSPs determine their pro-or antitumor activity. The present …
Heat shock factor 1 inhibition enhances the effects of modulated electro hyperthermia in a triple negative breast cancer mouse model
Female breast cancer is the most diagnosed cancer worldwide. Triple negative breast
cancer (TNBC) is the most aggressive type and there is no existing endocrine or targeted …
cancer (TNBC) is the most aggressive type and there is no existing endocrine or targeted …
Targeting the heat shock response induced by modulated electro-hyperthermia (mEHT) in cancer
Abstract The Heat Shock Response (HSR) is a cellular stress reaction crucial for cell survival
against stressors, including heat, in both healthy and cancer cells. Modulated electro …
against stressors, including heat, in both healthy and cancer cells. Modulated electro …
Non-thermal membrane effects of electromagnetic fields and therapeutic applications in oncology
P Wust, U Stein, P Ghadjar - International Journal of Hyperthermia, 2021 - Taylor & Francis
The temperature-independent effects of electromagnetic fields (EMF) have been
controversial for decades. Here, we critically analyze the available literature on non-thermal …
controversial for decades. Here, we critically analyze the available literature on non-thermal …
Exhaustion of protective heat shock response induces significant tumor damage by apoptosis after modulated electro-hyperthermia treatment of triple negative breast …
Simple Summary Breast cancer is one of the most frequent cancer types among women
worldwide. Triple-negative breast cancer is a highly aggressive breast cancer type with very …
worldwide. Triple-negative breast cancer is a highly aggressive breast cancer type with very …
Digoxin-Mediated Inhibition of Potential Hypoxia-Related Angiogenic Repair in Modulated Electro-Hyperthermia (mEHT)-Treated Murine Triple-Negative Breast …
SMZ Bokhari, K Aloss, PH Leroy Viana… - ACS Pharmacology & …, 2024 - ACS Publications
Triple-negative breast cancer (TNBC) is a highly aggressive breast cancer type with no
targeted therapy and hence limited treatment options. Modulated electrohyperthermia …
targeted therapy and hence limited treatment options. Modulated electrohyperthermia …
Heterogeneous heat absorption is complementary to radiotherapy
A Szasz - Cancers, 2022 - mdpi.com
Simple Summary This review shows the advantages of heterogeneous heating of selected
malignant cells in harmonic synergy with radiotherapy. The main clinical achievement of this …
malignant cells in harmonic synergy with radiotherapy. The main clinical achievement of this …
Modulated electro-hyperthermia resolves radioresistance of Panc1 pancreas adenocarcinoma and promotes DNA damage and apoptosis in vitro
The poor outcome of pancreas ductal adenocarcinomas (PDAC) is frequently linked to
therapy resistance. Modulated electro-hyperthermia (mEHT) generated by 13.56 MHz …
therapy resistance. Modulated electro-hyperthermia (mEHT) generated by 13.56 MHz …