Cardiac troponins: from myocardial infarction to chronic disease

KC Park, DC Gaze, PO Collinson… - Cardiovascular …, 2017 - academic.oup.com
Elucidation of the physiologically distinct subunits of troponin in 1973 greatly facilitated our
understanding of cardiac contraction. Although troponins are expressed in both skeletal and …

Circulating heart failure biomarkers beyond natriuretic peptides: review from the Biomarker Study Group of the Heart Failure Association (HFA), European Society of …

WC Meijers, A Bayes‐Genis, A Mebazaa… - European journal of …, 2021 - Wiley Online Library
New biomarkers are being evaluated for their ability to advance the management of patients
with heart failure. Despite a large pool of interesting candidate biomarkers, besides …

Exercise-induced cardiac troponin elevations: from underlying mechanisms to clinical relevance

VL Aengevaeren, AL Baggish, EH Chung, K George… - Circulation, 2021 - Am Heart Assoc
Serological assessment of cardiac troponins (cTn) is the gold standard to assess myocardial
injury in clinical practice. A greater magnitude of acutely or chronically elevated cTn …

How is cardiac troponin released from injured myocardium?

J Mair, B Lindahl, O Hammarsten… - … heart journal: acute …, 2018 - journals.sagepub.com
Cardiac troponin I and cardiac troponin T are nowadays the criterion biomarkers for the
laboratory diagnosis of acute myocardial infarction due to their very high sensitivities and …

Are there deleterious cardiac effects of acute and chronic endurance exercise?

TMH Eijsvogels, AB Fernandez… - Physiological …, 2016 - journals.physiology.org
Multiple epidemiological studies document that habitual physical activity reduces the risk of
atherosclerotic cardiovascular disease (ASCVD), and most demonstrate progressively lower …

Cardiac troponins: contemporary biological data and new methods of determination

A Chaulin - Vascular health and risk management, 2021 - Taylor & Francis
Laboratory diagnosis plays one of the key roles in the diagnosis of many diseases, including
cardiovascular diseases (CVD). The methods underlying the in vitro study of many CVD …

Troponin elevation in coronary vs. non-coronary disease

S Agewall, E Giannitsis, T Jernberg… - European heart …, 2011 - academic.oup.com
Acute myocardial infarction is defined as myocardial cell death due to prolonged myocardial
ischaemia. Cardiac troponins (cTn) are the most sensitive and specific biochemical markers …

Recommendations for the use of cardiac troponin measurement in acute cardiac care

K Thygesen, J Mair, H Katus, M Plebani… - European heart …, 2010 - academic.oup.com
The release of cardiomyocyte components, ie biomarkers, into the bloodstream in higher
than usual quantities indicates an ongoing pathological process. Thus, detection of elevated …

Exercise-induced cardiac troponin elevation: evidence, mechanisms, and implications

R Shave, A Baggish, K George, M Wood… - Journal of the American …, 2010 - jacc.org
Regular physical exercise is recommended for the primary prevention of cardiovascular
disease. Although the high prevalence of physical inactivity remains a formidable public …

Troponin: the biomarker of choice for the detection of cardiac injury

L Babuin, AS Jaffe - Cmaj, 2005 - Can Med Assoc
It has been known for 50 years that transaminase activity increases in patients with acute
myocardial infarction. With the development of creatine kinase (CK), biomarkers of cardiac …