Inflammatory processes in muscle injury and repair
JG Tidball - American Journal of Physiology-Regulatory …, 2005 - journals.physiology.org
Modified muscle use or injury can produce a stereotypic inflammatory response in which
neutrophils rapidly invade, followed by macrophages. This inflammatory response coincides …
neutrophils rapidly invade, followed by macrophages. This inflammatory response coincides …
[HTML][HTML] Immunobiology of inherited muscular dystrophies
JG Tidball, SS Welc… - Comprehensive …, 2018 - ncbi.nlm.nih.gov
The immune response to acute muscle damage is important for normal repair. However, in
chronic diseases such as many muscular dystrophies, the immune response can amplify …
chronic diseases such as many muscular dystrophies, the immune response can amplify …
Osteopontin promotes fibrosis in dystrophic mouse muscle by modulating immune cell subsets and intramuscular TGF-β
SA Vetrone, E Montecino-Rodriguez… - The Journal of …, 2009 - Am Soc Clin Investig
Duchenne muscular dystrophy (DMD) is an X-linked, degenerative muscle disease that is
exacerbated by secondary inflammation. Here, we characterized the immunological milieu …
exacerbated by secondary inflammation. Here, we characterized the immunological milieu …
Reduced necrosis of dystrophic muscle by depletion of host neutrophils, or blocking TNFα function with Etanercept in mdx mice
S Hodgetts, H Radley, M Davies, MD Grounds - Neuromuscular Disorders, 2006 - Elsevier
Necrosis of skeletal muscle fibres in the lethal childhood myopathy Duchenne Muscular
Dystrophy results from deficiency of the cell membrane associated protein, dystrophin. We …
Dystrophy results from deficiency of the cell membrane associated protein, dystrophin. We …
Anti‐TNFα (Remicade®) therapy protects dystrophic skeletal muscle from necrosis
MD Grounds, JO Torrisi - The FASEB Journal, 2004 - Wiley Online Library
Necrosis of skeletal muscle fibers in the lethal childhood myopathy Duchenne muscular
dystrophy (DMD) results from defects in the cell membrane‐associated protein dystrophin …
dystrophy (DMD) results from defects in the cell membrane‐associated protein dystrophin …
Mammalian animal models for Duchenne muscular dystrophy
R Willmann, S Possekel, J Dubach-Powell… - Neuromuscular …, 2009 - Elsevier
Duchenne muscular dystrophy (DMD) is a fatal neuromuscular disease that affects boys and
leads to early death. In the quest for new treatments that improve the quality of life and in the …
leads to early death. In the quest for new treatments that improve the quality of life and in the …
Proinflammatory cytokines and skeletal muscle
U Späte, PC Schulze - Current Opinion in Clinical Nutrition & …, 2004 - journals.lww.com
Pronounced catabolic effects of proinflammatory cytokines in various tissues contribute to
local catabolism, with progressive atrophic alterations of the skeletal muscle in chronic …
local catabolism, with progressive atrophic alterations of the skeletal muscle in chronic …
Sildenafil reduces respiratory muscle weakness and fibrosis in the mdx mouse model of Duchenne muscular dystrophy
JM Percival, NP Whitehead, ME Adams… - The Journal of …, 2012 - Wiley Online Library
Duchenne muscular dystrophy (DMD) is the most common form of muscular dystrophy
caused by mutations in the dystrophin gene. Loss of dystrophin initiates a progressive …
caused by mutations in the dystrophin gene. Loss of dystrophin initiates a progressive …
Research priorities for patients with heart failure and central sleep apnea. An official American Thoracic Society research statement
Background: Central sleep apnea (CSA) is common among patients with heart failure and
has been strongly linked to adverse outcomes. However, progress toward improving …
has been strongly linked to adverse outcomes. However, progress toward improving …
Cytokines in muscle damage
Multiple cellular and molecular processes are rapidly activated following skeletal muscle
damage to restore normal muscle structure and function. These processes typically involve …
damage to restore normal muscle structure and function. These processes typically involve …