Appraising the causal role of smoking in multiple diseases: A systematic review and meta-analysis of Mendelian randomization studies
SC Larsson, S Burgess - EBioMedicine, 2022 - thelancet.com
Background The causal association between cigarette smoking and several diseases
remains equivocal. The purpose of this study was to appraise the causal role of smoking in a …
remains equivocal. The purpose of this study was to appraise the causal role of smoking in a …
A meta‐review of “lifestyle psychiatry”: the role of exercise, smoking, diet and sleep in the prevention and treatment of mental disorders
There is increasing academic and clinical interest in how “lifestyle factors” traditionally
associated with physical health may also relate to mental health and psychological well …
associated with physical health may also relate to mental health and psychological well …
Acute COVID-19 severity and mental health morbidity trajectories in patient populations of six nations: an observational study
Background Long-term mental and physical health consequences of COVID-19 (long
COVID) are a persistent public health concern. Little is still known about the long-term …
COVID) are a persistent public health concern. Little is still known about the long-term …
Elevated C-reactive protein in patients with depression, independent of genetic, health, and psychosocial factors: results from the UK Biobank
MC Pitharouli, SP Hagenaars… - American Journal of …, 2021 - Am Psychiatric Assoc
Objective: The authors investigated the pathways (genetic, environmental, lifestyle, medical)
leading to inflammation in major depressive disorder using C-reactive protein (CRP) …
leading to inflammation in major depressive disorder using C-reactive protein (CRP) …
Inference of chronic obstructive pulmonary disease with deep learning on raw spirograms identifies new genetic loci and improves risk models
Chronic obstructive pulmonary disease (COPD), the third leading cause of death worldwide,
is highly heritable. While COPD is clinically defined by applying thresholds to summary …
is highly heritable. While COPD is clinically defined by applying thresholds to summary …
Smoking, alcohol consumption, and 24 gastrointestinal diseases: Mendelian randomization analysis
Background: Whether the positive associations of smoking and alcohol consumption with
gastrointestinal diseases are causal is uncertain. We conducted this Mendelian …
gastrointestinal diseases are causal is uncertain. We conducted this Mendelian …
Minimal phenotyping yields genome-wide association signals of low specificity for major depression
Minimal phenotyping refers to the reliance on the use of a small number of self-reported
items for disease case identification, increasingly used in genome-wide association studies …
items for disease case identification, increasingly used in genome-wide association studies …
[HTML][HTML] Dissecting the shared genetic architecture of suicide attempt, psychiatric disorders, and known risk factors
Background Suicide is a leading cause of death worldwide, and nonfatal suicide attempts,
which occur far more frequently, are a major source of disability and social and economic …
which occur far more frequently, are a major source of disability and social and economic …
Risk factors for human papillomavirus infection, cervical intraepithelial neoplasia and cervical cancer: an umbrella review and follow-up Mendelian randomisation …
Background Persistent infection by oncogenic human papillomavirus (HPV) is necessary
although not sufficient for development of cervical cancer. Behavioural, environmental, or …
although not sufficient for development of cervical cancer. Behavioural, environmental, or …
Exploring causal correlations between inflammatory cytokines and systemic lupus erythematosus: A Mendelian randomization
M Xiang, Y Wang, Z Gao, J Wang, Q Chen… - Frontiers in …, 2023 - frontiersin.org
Objectives Previous studies have reported that a few inflammatory cytokines have
associations with systemic lupus erythematosus (SLE)—for example, IL-6, IL-17, and …
associations with systemic lupus erythematosus (SLE)—for example, IL-6, IL-17, and …