Macrophages: the good, the bad, and the gluttony
Macrophages are dynamic cells that play critical roles in the induction and resolution of
sterile inflammation. In this review, we will compile and interpret recent findings on the …
sterile inflammation. In this review, we will compile and interpret recent findings on the …
The pathogenesis of psoriatic arthritis
DJ Veale, U Fearon - The Lancet, 2018 - thelancet.com
Psoriatic arthritis is a chronic, immune-mediated, inflammatory arthropathy that presents with
inflammation of the joints and entheses, including those of the axial skeleton, and is …
inflammation of the joints and entheses, including those of the axial skeleton, and is …
Macrophage M1/M2 polarization and rheumatoid arthritis: a systematic review
S Tardito, G Martinelli, S Soldano, S Paolino… - Autoimmunity …, 2019 - Elsevier
Background and aim Rheumatoid arthritis (RA) is a chronic autoimmune inflammatory
disease; the clinical manifestations are correlated with continuum multiarticular synovitis …
disease; the clinical manifestations are correlated with continuum multiarticular synovitis …
Macrophage plasticity and polarization: in vivo veritas
A Sica, A Mantovani - The Journal of clinical investigation, 2012 - Am Soc Clin Investig
Diversity and plasticity are hallmarks of cells of the monocyte-macrophage lineage. In
response to IFNs, Toll-like receptor engagement, or IL-4/IL-13 signaling, macrophages …
response to IFNs, Toll-like receptor engagement, or IL-4/IL-13 signaling, macrophages …
Immune modulation of some autoimmune diseases: the critical role of macrophages and neutrophils in the innate and adaptive immunity
KC Navegantes, R de Souza Gomes… - Journal of translational …, 2017 - Springer
Macrophages and neutrophils are key components involved in the regulation of numerous
chronic inflammatory diseases, infectious disorders, and especially certain autoimmune …
chronic inflammatory diseases, infectious disorders, and especially certain autoimmune …
Spondyloarthritis
M Dougados, D Baeten - The Lancet, 2011 - thelancet.com
Spondyloarthritis is a group of several related but phenotypically distinct disorders: psoriatic
arthritis, arthritis related to inflammatory bowel disease, reactive arthritis, a subgroup of …
arthritis, arthritis related to inflammatory bowel disease, reactive arthritis, a subgroup of …
Emerging role of targeting macrophages in rheumatoid arthritis: focus on polarization, metabolism and apoptosis
X Yang, Y Chang, W Wei - Cell proliferation, 2020 - Wiley Online Library
Macrophages maintain a dynamic balance in physiology. Various known or unknown
microenvironmental signals influence the polarization, activation and death of macrophages …
microenvironmental signals influence the polarization, activation and death of macrophages …
Systematic validation of specific phenotypic markers for in vitro polarized human macrophages
CA Ambarus, S Krausz, M van Eijk, J Hamann… - Journal of …, 2012 - Elsevier
BACKGROUND: Polarization of macrophages by specific micro-environmental conditions
impacts upon their function following subsequent activation. This study aimed to …
impacts upon their function following subsequent activation. This study aimed to …
Analysis of IL-17+cells in facet joints of patients with spondyloarthritis suggests that the innate immune pathway might be of greater relevance than the Th17-mediated …
H Appel, R Maier, P Wu, R Scheer, A Hempfing… - Arthritis research & …, 2011 - Springer
Introduction In this study, we analysed the number of IL-17+ cells in facet joints, in the
peripheral blood (PB) and synovial fluid (SF) of spondyloarthritis (SpA) patients and …
peripheral blood (PB) and synovial fluid (SF) of spondyloarthritis (SpA) patients and …
Macrophages with regulatory functions, a possible new therapeutic perspective in autoimmune diseases
P Di Benedetto, P Ruscitti, Z Vadasz, E Toubi… - Autoimmunity …, 2019 - Elsevier
Macrophages are pivotal cells involved in chronic inflammatory and autoimmune diseases.
In fact, during these diseases, activated macrophages may play a critical role, promoting the …
In fact, during these diseases, activated macrophages may play a critical role, promoting the …