Chemical design and synthesis of functionalized probes for imaging and treating tumor hypoxia

J Liu, W Bu, J Shi - Chemical reviews, 2017 - ACS Publications
Hypoxia development in tumor is closely associated with its increased aggressiveness and
strong resistance to therapy, leading to the poor prognosis in several cancer types …

[HTML][HTML] Applications of supramolecular anion recognition

N Busschaert, C Caltagirone, W Van Rossom… - Chemical …, 2015 - ACS Publications
The study of the complexation of anions, from its beginnings in the late 1960s and 1970s,(1-
3) has moved on from being an area solely of academic interest to a fundamental pillar of …

Small molecule-based ratiometric fluorescence probes for cations, anions, and biomolecules

M HeeáLee, J SeungáKim - Chemical Society Reviews, 2015 - pubs.rsc.org
Quantitative determination of specific analytes is essential for a variety of applications
ranging from life sciences to environmental monitoring. Optical sensing allows non-invasive …

Design strategies for water-soluble small molecular chromogenic and fluorogenic probes

X Li, X Gao, W Shi, H Ma - Chemical reviews, 2014 - ACS Publications
Chromogenic and fluorogenic probes may be described as the reagents that can interact
with analytes (targets) accompanied by the changes of their spectroscopic (chromogenic, or …

Biological applications of supramolecular assemblies designed for excitation energy transfer

HQ Peng, LY Niu, YZ Chen, LZ Wu, CH Tung… - Chemical …, 2015 - ACS Publications
Absorption of light by a molecule (donor, D) generates an excited state, which may
subsequently transfer the excitation to another chromophore (acceptor, A) in the vicinity …

Single-cell metabolomics: analytical and biological perspectives

R Zenobi - Science, 2013 - science.org
Background In recent years, there has been a surge in the development and application of
single-cell genomics, transcriptomics, proteomics, and metabolomics. The metabolome is …

Metal coordination in photoluminescent sensing

Z Liu, W He, Z Guo - Chemical Society Reviews, 2013 - pubs.rsc.org
Coordination chemistry plays an essential role in the design of photoluminescent probes for
metal ions. Metal coordination to organic dyes induces distinct optical responses which …

BODIPY-based ratiometric fluorescent sensor for highly selective detection of glutathione over cysteine and homocysteine

LY Niu, YS Guan, YZ Chen, LZ Wu… - Journal of the …, 2012 - ACS Publications
We report a ratiometric fluorescent sensor based on monochlorinated BODIPY for highly
selective detection of glutathione (GSH) over cysteine (Cys)/homocysteine (Hcy). The …

Chromogenic/fluorogenic ensemble chemosensing systems

J Wu, B Kwon, W Liu, EV Anslyn, P Wang… - Chemical …, 2015 - ACS Publications
Nature has endowed human beings with many useful functions, by virtue of supramolecular
chemistry. As is well-known, nature can self-assemble relatively small molecular precursors …

Current developments of coumarin compounds in medicinal chemistry

XM Peng, G LV Damu, C He Zhou - Current pharmaceutical …, 2013 - benthamdirect.com
Coumarin compounds represent an important type of naturally occurring and synthetic
oxygen-containing heterocycles with typical benzopyrone framework. This type of special …