Chemical design and synthesis of functionalized probes for imaging and treating tumor hypoxia
Hypoxia development in tumor is closely associated with its increased aggressiveness and
strong resistance to therapy, leading to the poor prognosis in several cancer types …
strong resistance to therapy, leading to the poor prognosis in several cancer types …
[HTML][HTML] Applications of supramolecular anion recognition
N Busschaert, C Caltagirone, W Van Rossom… - Chemical …, 2015 - ACS Publications
The study of the complexation of anions, from its beginnings in the late 1960s and 1970s,(1-
3) has moved on from being an area solely of academic interest to a fundamental pillar of …
3) has moved on from being an area solely of academic interest to a fundamental pillar of …
Small molecule-based ratiometric fluorescence probes for cations, anions, and biomolecules
M HeeáLee, J SeungáKim - Chemical Society Reviews, 2015 - pubs.rsc.org
Quantitative determination of specific analytes is essential for a variety of applications
ranging from life sciences to environmental monitoring. Optical sensing allows non-invasive …
ranging from life sciences to environmental monitoring. Optical sensing allows non-invasive …
Design strategies for water-soluble small molecular chromogenic and fluorogenic probes
X Li, X Gao, W Shi, H Ma - Chemical reviews, 2014 - ACS Publications
Chromogenic and fluorogenic probes may be described as the reagents that can interact
with analytes (targets) accompanied by the changes of their spectroscopic (chromogenic, or …
with analytes (targets) accompanied by the changes of their spectroscopic (chromogenic, or …
Biological applications of supramolecular assemblies designed for excitation energy transfer
Absorption of light by a molecule (donor, D) generates an excited state, which may
subsequently transfer the excitation to another chromophore (acceptor, A) in the vicinity …
subsequently transfer the excitation to another chromophore (acceptor, A) in the vicinity …
Single-cell metabolomics: analytical and biological perspectives
R Zenobi - Science, 2013 - science.org
Background In recent years, there has been a surge in the development and application of
single-cell genomics, transcriptomics, proteomics, and metabolomics. The metabolome is …
single-cell genomics, transcriptomics, proteomics, and metabolomics. The metabolome is …
Metal coordination in photoluminescent sensing
Coordination chemistry plays an essential role in the design of photoluminescent probes for
metal ions. Metal coordination to organic dyes induces distinct optical responses which …
metal ions. Metal coordination to organic dyes induces distinct optical responses which …
BODIPY-based ratiometric fluorescent sensor for highly selective detection of glutathione over cysteine and homocysteine
We report a ratiometric fluorescent sensor based on monochlorinated BODIPY for highly
selective detection of glutathione (GSH) over cysteine (Cys)/homocysteine (Hcy). The …
selective detection of glutathione (GSH) over cysteine (Cys)/homocysteine (Hcy). The …
Chromogenic/fluorogenic ensemble chemosensing systems
J Wu, B Kwon, W Liu, EV Anslyn, P Wang… - Chemical …, 2015 - ACS Publications
Nature has endowed human beings with many useful functions, by virtue of supramolecular
chemistry. As is well-known, nature can self-assemble relatively small molecular precursors …
chemistry. As is well-known, nature can self-assemble relatively small molecular precursors …
Current developments of coumarin compounds in medicinal chemistry
XM Peng, G LV Damu, C He Zhou - Current pharmaceutical …, 2013 - benthamdirect.com
Coumarin compounds represent an important type of naturally occurring and synthetic
oxygen-containing heterocycles with typical benzopyrone framework. This type of special …
oxygen-containing heterocycles with typical benzopyrone framework. This type of special …