Melanomas arising in the uveal tract of the eye are a rare form of the disease with a biology
and clinical phenotype distinct from their more common cutaneous counterparts. Treatment …

Introduction Metastatic uveal melanoma is associated with poor prognosis and few treatment
options. Tebentafusp recently became the first FDA-approved agent for metastatic uveal …

Uveal melanoma (UM) is a type of intraocular tumor with a propensity to disseminate to the
liver. Despite the identification of the early driver mutations during the development of the …

Uveal melanoma (UM) has well-characterised somatic copy number alterations (SCNA) in
chromosomes 1, 3, 6 and 8, in addition to mutations in GNAQ, GNA11, CYSLTR2, PLCB4 …

Objective To analyse ocular and systemic findings of patients presenting with systemic
metastasis. Methods and analysis It is an international, multicentre, internet-enabled, registry …

Background: Uveal melanoma (UM) is the most common primary intraocular malignancy in
adults. Monosomy 3 and BAP1 mutation are strong prognostic factors predicting metastatic …

Uveal melanoma (UM) is an aggressive and deadly neoplasm. In recent decades, great
efforts have been made to obtain a more comprehensive understanding of genetics …

Uveal melanoma (UM) is a rare tumour of the eye, characterised by a high propensity to
metastasise in half of all patients, most frequently to the liver. Although there are effective …

Uveal melanoma (UM), arising from intraocular melanocytes, poses a complex clinical
challenge with a substantial risk of distant metastasis, often to the liver. Molecular profiling …

Choroidal melanomas are the most common ocular malignant tumors worldwide. The onset
of such tumors is insidious, such that affected patients often have no pain or obvious …