Perihaematomal oedema (PHO) is an important pathophysiological marker of secondary
injury in intracerebral haemorrhage (ICH). In this Review, we describe a novel method to …

Prevalence of mental disorders, including major depressive disorder (MDD), bipolar
disorder (BD) and schizophrenia (SZ) are increasing at alarming rates in our societies …

Major depressive disorder (MDD) is a chronic and recurrent psychiatric condition
characterized by depressed mood, social isolation and anhedonia. It will affect 20% of …

Cerebral autoregulation (CA) is integral to the delicate process of maintaining stable
cerebral perfusion and brain tissue oxygenation against changes in arterial blood pressure …

Background Sex differences in major cardiovascular risk factors for incident (fatal or non-
fatal) all-cause dementia were assessed in the UK Biobank. The effects of these risk factors …

Sex is an important determinant of brain microvessels (MVs) function and susceptibility to
cerebrovascular and neurological diseases, but underlying mechanisms are unclear. Using …

Intact, coordinated, and precisely regulated cerebrovascular responses are required for the
maintenance of cerebral metabolic homeostasis, adequate perfusion, oxygen delivery, and …

Background Impaired cerebral autoregulation may predispose patients to cerebral
hypoperfusion during cardiopulmonary bypass (CPB). The purpose of this study was to …

Sex differences exist in how cerebral blood vessels function under both physiological and
pathological conditions, contributing to observed sex differences in risk and outcomes of …

Young women exhibit higher prevalence of orthostatic hypotension with presyncopal
symptoms compared to men. These symptoms could be influenced by an attenuated ability …