Meta-hallmarks of aging and cancer

C López-Otín, F Pietrocola, D Roiz-Valle, L Galluzzi… - Cell metabolism, 2023 - cell.com
Both aging and cancer are characterized by a series of partially overlapping" hallmarks" that
we subject here to a meta-analysis. Several hallmarks of aging (ie, genomic instability …

Contemporary medical, device, and surgical therapies for obesity in adults

CM Perdomo, RV Cohen, P Sumithran, K Clément… - The Lancet, 2023 - thelancet.com
The goal of obesity management is to improve health. Sustained weight loss of more than
10% overall bodyweight improves many of the complications associated with obesity (eg …

A 2022 update on the epidemiology of obesity and a call to action: as its twin COVID-19 pandemic appears to be receding, the obesity and dysmetabolism pandemic …

C Boutari, CS Mantzoros - Metabolism, 2022 - Elsevier
The WHO just released in May 2022 a report on the state of the obesity pandemic in Europe,
stating that 60% of citizens in the area of Europe are either overweight or obese, and …

Cancer statistics for African American/black people 2022

AN Giaquinto, KD Miller, KY Tossas… - CA: a cancer journal …, 2022 - Wiley Online Library
Abstract African American/Black individuals have a disproportionate cancer burden,
including the highest mortality and the lowest survival of any racial/ethnic group for most …

[PDF][PDF] Endometrial cancer: ESMO Clinical Practice Guideline for diagnosis, treatment and follow-up

A Oaknin, TJ Bosse, CL Creutzberg, G Giornelli… - Annals of oncology, 2022 - Elsevier
Highlights•This ESMO Clinical Practice Guideline provides key recommendations for
managing endometrial cancer.•The guideline covers clinical and pathological diagnosis …

The role of lipids in cancer progression and metastasis

M Martin-Perez, U Urdiroz-Urricelqui, C Bigas… - Cell metabolism, 2022 - cell.com
Lipids have essential biological functions in the body (eg, providing energy storage, acting
as a signaling molecule, and being a structural component of membranes); however, an …

Obesity and cancer: a current overview of epidemiology, pathogenesis, outcomes, and management

S Pati, W Irfan, A Jameel, S Ahmed, RK Shahid - Cancers, 2023 - mdpi.com
Simple Summary Obesity has been linked to several common cancers including breast,
colorectal, esophageal, kidney, gallbladder, uterine, pancreatic, and liver cancer. Obesity …

Neutrophil phenotypes and functions in cancer: A consensus statement

DF Quail, B Amulic, M Aziz, BJ Barnes… - Journal of Experimental …, 2022 - rupress.org
Neutrophils are the first responders to infection and inflammation and are thus a critical
component of innate immune defense. Understanding the behavior of neutrophils as they …

Reassessing human adipose tissue

AM Cypess - New England Journal of Medicine, 2022 - Mass Medical Soc
Reassessing Human Adipose Tissue Adipose tissue can more than double in mass and
then return to baseline. This review discusses the functional roles of human white and brown …

Integrative oncology: Addressing the global challenges of cancer prevention and treatment

JJ Mao, GG Pillai, CJ Andrade… - CA: A Cancer …, 2022 - Wiley Online Library
The increase in cancer incidence and mortality is challenging current cancer care delivery
globally, disproportionally affecting low‐and middle‐income countries (LMICs) when it …