[HTML][HTML] Functional polarization of tumor-associated macrophages dictated by metabolic reprogramming
W Zeng, F Li, S Jin, PC Ho, PS Liu, X Xie - Journal of Experimental & …, 2023 - Springer
Macrophages are highly plastic in different tissues and can differentiate into functional
subpopulations under different stimuli. Tumor-associated macrophages (TAMs) are one of …
subpopulations under different stimuli. Tumor-associated macrophages (TAMs) are one of …
[HTML][HTML] New insights into the role of adipocytes in pancreatic cancer progression: paving the way towards novel therapeutic targets
Pancreatic cancer (PC) remains one of the most lethal malignancies across the world, which
is due to delayed diagnosis and resistance to current therapies. The interactions between …
is due to delayed diagnosis and resistance to current therapies. The interactions between …
[HTML][HTML] Host obesity alters the ovarian tumor immune microenvironment and impacts response to standard of care chemotherapy
Y Liu, J Yang, TS Hilliard, Z Wang, J Johnson… - Journal of Experimental …, 2023 - Springer
Background The majority of women with epithelial ovarian cancer (OvCa) are diagnosed
with metastatic disease, resulting in a poor 5-year survival of 31%. Obesity is a recognized …
with metastatic disease, resulting in a poor 5-year survival of 31%. Obesity is a recognized …
[HTML][HTML] Lipocalin-2 promotes adipose–macrophage interactions to shape peripheral and central inflammatory responses in experimental autoimmune …
F Sciarretta, V Ceci, M Tiberi, F Zaccaria, H Li… - Molecular …, 2023 - Elsevier
Objective Accumulating evidence suggests that dysfunctional adipose tissue (AT) plays a
major role in the risk of developing multiple sclerosis (MS), the most common immune …
major role in the risk of developing multiple sclerosis (MS), the most common immune …
[HTML][HTML] Outcomes in breast cancer—does ethnicity matter?
YS Yap - ESMO open, 2023 - Elsevier
Ethnic or racial differences in breast cancer (BC) survival outcomes have been reported, but
current data are largely restricted to comparisons between African Americans and non …
current data are largely restricted to comparisons between African Americans and non …
[HTML][HTML] Body mass index, C-reactive protein, and pancreatic cancer: A Mendelian randomization analysis to investigate causal pathways
Z Li, L Jin, L Xia, X Li, Y Guan, H He - Frontiers in Oncology, 2023 - frontiersin.org
Aim To explore whether C-reactive protein (CRP) mediates the risk of body mass index
(BMI) in pancreatic cancer (PC) and calculate the mediate proportion of CRP in this possible …
(BMI) in pancreatic cancer (PC) and calculate the mediate proportion of CRP in this possible …
[HTML][HTML] Impact of intestinal microenvironments in obesity and bariatric surgery on shaping macrophages
M Leyderman, JR Wilmore, T Shope… - …, 2023 - journals.lww.com
Obesity is associated with alterations in tissue composition, systemic cellular metabolism,
and low-grade chronic inflammation. Macrophages are heterogenous innate immune cells …
and low-grade chronic inflammation. Macrophages are heterogenous innate immune cells …
A preliminary mechanistic exploration of the effect of leptin on the docetaxel sensitivity of MDA‑MB‑231 triple‑negative breast cancer cells
S Gao, S Ding, Z Tang - Molecular and Clinical …, 2024 - spandidos-publications.com
Breast cancer is a common tumor encountered in women, and triple‑negative breast cancer
(TNBC) has an extremely poor prognosis. The effect of leptin on the docetaxel sensitivity of …
(TNBC) has an extremely poor prognosis. The effect of leptin on the docetaxel sensitivity of …
Somatic evolution of Cancer: A new synthesis
U Baing, R Kharate, M Watve - 2023 - preprints.org
Cancers have been interpreted either as somatic evolution of cheater cells that escape
replication regulation or alternatively as non-healing wounds. Both the interpretations have …
replication regulation or alternatively as non-healing wounds. Both the interpretations have …
[HTML][HTML] Obesity of children and adults-pandemic of the 21st century
D Panasiuk, P Szponarowicz, E Panek… - Journal of Education …, 2023 - apcz.umk.pl
Objective: The aim of the study was to draw attention to the problem of overweight and
obesity among children and adults. Another important aspect of this article was to indicate …
obesity among children and adults. Another important aspect of this article was to indicate …