Runs of homozygosity: current knowledge and applications in livestock
E Peripolli, DP Munari, M Silva, ALF Lima… - Animal …, 2017 - Wiley Online Library
This review presents a broader approach to the implementation and study of runs of
homozygosity (ROH) in animal populations, focusing on identifying and characterizing ROH …
homozygosity (ROH) in animal populations, focusing on identifying and characterizing ROH …
Molecular tools and analytical approaches for the characterization of farm animal genetic diversity
JA Lenstra, LF Groeneveld, H Eding… - Animal …, 2012 - Wiley Online Library
Genetic studies of livestock populations focus on questions of domestication, within‐and
among‐breed diversity, breed history and adaptive variation. In this review, we describe the …
among‐breed diversity, breed history and adaptive variation. In this review, we describe the …
Inbreeding and runs of homozygosity: A possible solution to an old problem
Quantifying human, plant and livestock inbreeding has been an important goal of
evolutionary biologists and agricultural scientists for nearly a century, and methods to do so …
evolutionary biologists and agricultural scientists for nearly a century, and methods to do so …
A publicly available repository of ROH islands reveals signatures of selection in different livestock and pet species
W Gorssen, R Meyermans, S Janssens… - Genetics Selection …, 2021 - Springer
Background Runs of homozygosity (ROH) have become the state-of-the-art method for
analysis of inbreeding in animal populations. Moreover, ROH are suited to detect signatures …
analysis of inbreeding in animal populations. Moreover, ROH are suited to detect signatures …
Estimates of autozygosity derived from runs of homozygosity: empirical evidence from selected cattle populations
Using genome‐wide SNP data, we calculated genomic inbreeding coefficients (FROH> 1
Mb, FROH> 2 Mb, FROH> 8 Mb and FROH> 16 Mb) derived from runs of homozygosity …
Mb, FROH> 2 Mb, FROH> 8 Mb and FROH> 16 Mb) derived from runs of homozygosity …
[HTML][HTML] Genome-wide mapping and estimation of inbreeding depression of semen quality traits in a cattle population
Inbreeding depression is known to affect quantitative traits such as male fertility and sperm
quality, but the genetic basis for these associations is poorly understood. Most studies have …
quality, but the genetic basis for these associations is poorly understood. Most studies have …
Genomic data of different resolutions reveal consistent inbreeding estimates but contrasting homozygosity landscapes for the threatened Aotearoa New Zealand hihi
Inbreeding can lead to a loss of heterozygosity in a population and when combined with
genetic drift may reduce the adaptive potential of a species. However, there is uncertainty …
genetic drift may reduce the adaptive potential of a species. However, there is uncertainty …
[HTML][HTML] The pattern of runs of homozygosity and genomic inbreeding in world-wide sheep populations
Genome-wide pattern of runs of homozygosity (ROH) across ovine genome can provide a
useful resource for studying diversity and demography history in sheep. We analyzed 50 k …
useful resource for studying diversity and demography history in sheep. We analyzed 50 k …
Population structure and genetic diversity of sheep breeds in the Kyrgyzstan
T Deniskova, A Dotsev, E Lushihina, A Shakhin… - Frontiers in …, 2019 - frontiersin.org
Sheep are a main livestock species of Kyrgyzstan, a Central Asian country with
predominating mountain terrain. The current gene pool of local sheep resources has been …
predominating mountain terrain. The current gene pool of local sheep resources has been …
Misidentification of runs of homozygosity islands in cattle caused by interference with copy number variation or large intermarker distances
Background Runs of homozygosity (ROH) islands are stretches of homozygous sequence in
the genome of a large proportion of individuals in a population. Algorithms for the detection …
the genome of a large proportion of individuals in a population. Algorithms for the detection …