Tackling the emerging threat of antifungal resistance to human health
Invasive fungal infections pose an important threat to public health and are an under-
recognized component of antimicrobial resistance, an emerging crisis worldwide. Across a …
recognized component of antimicrobial resistance, an emerging crisis worldwide. Across a …
The importance of antimicrobial resistance in medical mycology
Prior to the SARS-CoV-2 pandemic, antibiotic resistance was listed as the major global
health care priority. Some analyses, including the O'Neill report, have predicted that deaths …
health care priority. Some analyses, including the O'Neill report, have predicted that deaths …
The rapid emergence of antifungal-resistant human-pathogenic fungi
SR Lockhart, A Chowdhary, JAW Gold - Nature Reviews Microbiology, 2023 - nature.com
During recent decades, the emergence of pathogenic fungi has posed an increasing public
health threat, particularly given the limited number of antifungal drugs available to treat …
health threat, particularly given the limited number of antifungal drugs available to treat …
Structural and mechanistic insights into fungal β-1, 3-glucan synthase FKS1
X Hu, P Yang, C Chai, J Liu, H Sun, Y Wu, M Zhang… - Nature, 2023 - nature.com
The membrane-integrated synthase FKS is involved in the biosynthesis of β-1, 3-glucan, the
core component of the fungal cell wall,. FKS is the target of widely prescribed antifungal …
core component of the fungal cell wall,. FKS is the target of widely prescribed antifungal …
Antifungal Drug Resistance: Molecular Mechanisms in Candida albicans and Beyond
Fungal infections are a major contributor to infectious disease-related deaths across the
globe. Candida species are among the most common causes of invasive mycotic disease …
globe. Candida species are among the most common causes of invasive mycotic disease …
Biofilm of Candida albicans: formation, regulation and resistance
R Pereira, RO Dos Santos Fontenelle… - Journal of Applied …, 2021 - academic.oup.com
Candida albicans is the most common human fungal pathogen, causing infections that
range from mucous membranes to systemic infections. The present article provides an …
range from mucous membranes to systemic infections. The present article provides an …
Twenty Years of the SENTRY Antifungal Surveillance Program: Results for Candida Species From 1997–2016
MA Pfaller, DJ Diekema, JD Turnidge… - Open forum …, 2019 - academic.oup.com
Background The emergence of antifungal resistance threatens effective treatment of
invasive fungal infection (IFI). Invasive candidiasis is the most common health care …
invasive fungal infection (IFI). Invasive candidiasis is the most common health care …
[HTML][HTML] Invasive candidiasis
PG Pappas, MS Lionakis, MC Arendrup… - Nature Reviews …, 2018 - nature.com
Invasive candidiasis is an important health-care-associated fungal infection that can be
caused by several Candida spp.; the most common species is Candida albicans, but the …
caused by several Candida spp.; the most common species is Candida albicans, but the …
Candidemia and invasive candidiasis
TP McCarty, CM White, PG Pappas - Infectious Disease Clinics, 2021 - id.theclinics.com
Invasive infection caused by Candida species is a condition associated with medical
progress. It is a common health care–associated infection (HAI), and is widely recognized as …
progress. It is a common health care–associated infection (HAI), and is widely recognized as …
[HTML][HTML] Resistance of Candida to azoles and echinocandins worldwide
KE Pristov, MA Ghannoum - Clinical Microbiology and Infection, 2019 - Elsevier
Background Recently there has been an increase in Candida infections worldwide. A
handful of species in the genus Candida are opportunistic pathogens and have been known …
handful of species in the genus Candida are opportunistic pathogens and have been known …