This review focuses on neuropeptides and peptide hormones, the largest and most diverse
class of neuroactive substances, known in Drosophila and other animals to play roles in …

An adult animal consists of cells of vastly different size and activity, but the regulation of cell
size remains poorly understood. Recent studies uncovering some of the signaling pathways …

An obstacle to the use of graphene as an alternative to silicon electronics has been the
absence of an energy gap between its conduction and valence bands, which makes it …

The symbiotic microbiota profoundly affect many aspects of host physiology; however, the
molecular mechanisms underlying host-microbe cross-talk are largely unknown. Here, we …

Wing polyphenism is an evolutionarily successful feature found in a wide range of insects.
Long-winged morphs can fly, which allows them to escape adverse habitats and track …

The steroid hormone ecdysone is the central regulator of insect developmental transitions.
Recent new advances in our understanding of ecdysone action have relied heavily on the …

To elucidate mechanisms underlying the complex relationships between a host and its
microbiota, we used the genetically tractable model Drosophila melanogaster. Consistent …

For organisms to coordinate their growth and development with nutrient availability, they
must be able to sense nutrient levels in their environment. Here, we review select nutrient …

Body size is a key feature of organisms and varies continuously because of the effects of
natural selection on the size‐dependency of resource acquisition and mortality rates. This …

Multicellular animals match costly activities, such as growth and reproduction, to the
environment through nutrient-sensing pathways. The insulin/IGF signaling (IIS) pathway …