Progression of cerebral amyloid angiopathy: a pathophysiological framework
EA Koemans, JP Chhatwal, SJ van Veluw… - The Lancet …, 2023 - thelancet.com
Cerebral amyloid angiopathy, which is defined by cerebrovascular deposition of amyloid β,
is a common age-related small vessel pathology associated with intracerebral haemorrhage …
is a common age-related small vessel pathology associated with intracerebral haemorrhage …
Multifaceted roles of APOE in Alzheimer disease
RJ Jackson, BT Hyman, A Serrano-Pozo - Nature Reviews Neurology, 2024 - nature.com
For the past three decades, apolipoprotein E (APOE) has been known as the single greatest
genetic modulator of sporadic Alzheimer disease (AD) risk, influencing both the average age …
genetic modulator of sporadic Alzheimer disease (AD) risk, influencing both the average age …
Machine learning: new ideas and tools in environmental science and engineering
The rapid increase in both the quantity and complexity of data that are being generated daily
in the field of environmental science and engineering (ESE) demands accompanied …
in the field of environmental science and engineering (ESE) demands accompanied …
Blood-brain barrier dysfunction in normal aging and neurodegeneration: mechanisms, impact, and treatments
AV Andjelkovic, M Situ, AF Citalan-Madrid… - Stroke, 2023 - Am Heart Assoc
Cerebral endothelial cells and their linking tight junctions form a unique, dynamic and multi-
functional interface, the blood-brain barrier (BBB). The endothelium is regulated by …
functional interface, the blood-brain barrier (BBB). The endothelium is regulated by …
A practical approach to the management of cerebral amyloid angiopathy
Cerebral amyloid angiopathy is a common small vessel disease in the elderly involving
vascular amyloid-β deposition. Cerebral amyloid angiopathy is one of the leading causes of …
vascular amyloid-β deposition. Cerebral amyloid angiopathy is one of the leading causes of …
Neuropathological correlates of cortical superficial siderosis in cerebral amyloid angiopathy
Cortical superficial siderosis is an established haemorrhagic neuroimaging marker of
cerebral amyloid angiopathy. In fact, cortical superficial siderosis is emerging as a strong …
cerebral amyloid angiopathy. In fact, cortical superficial siderosis is emerging as a strong …
Clinical considerations in early-onset cerebral amyloid angiopathy
Cerebral amyloid angiopathy (CAA) is an important cerebral small vessel disease
associated with brain haemorrhage and cognitive change. The commonest form, sporadic …
associated with brain haemorrhage and cognitive change. The commonest form, sporadic …
Vessels sing their ARIAs: the role of vascular amyloid in the age of aducanumab
L Sveikata, A Charidimou, A Viswanathan - Stroke, 2022 - Am Heart Assoc
We review the implications of the recently approved aducanumab amyloid-β immunotherapy
for treating Alzheimer disease with comorbid cerebral amyloid angiopathy. In clinical trials …
for treating Alzheimer disease with comorbid cerebral amyloid angiopathy. In clinical trials …
Relationship of apolipoprotein E with Alzheimer's disease and other neurological disorders: an updated review
T Lou, B Tao, M Chen - Neuroscience, 2023 - Elsevier
Alzheimer's disease (AD) and other neurodegenerative diseases, for which there is no
effective cure, cause great social burden. Apolipoprotein E (APOE) is an important lipid …
effective cure, cause great social burden. Apolipoprotein E (APOE) is an important lipid …
[HTML][HTML] Genetic architecture of common non-Alzheimer's disease dementias
Frontotemporal dementia (FTD), dementia with Lewy bodies (DLB) and vascular dementia
(VaD) are the most common forms of dementia after Alzheimer's disease (AD). The …
(VaD) are the most common forms of dementia after Alzheimer's disease (AD). The …