Plant‐derived vesicle‐like nanoparticles as promising biotherapeutic tools: Present and future

J Feng, Q Xiu, Y Huang, Z Troyer, B Li… - Advanced …, 2023 - Wiley Online Library
Extracellular vesicles (EVs) are heterogeneous, phospholipid bilayer‐enclosed biological
particles that regulate cell communication by molecular cargo delivery and surface …

[HTML][HTML] New strategies of neurodegenerative disease treatment with extracellular vesicles (EVs) derived from mesenchymal stem cells (MSCs)

CP Palanisamy, JJ Pei, P Alugoju, NVA Anthikapalli… - Theranostics, 2023 - ncbi.nlm.nih.gov
Neurodegenerative diseases are characterized by the progressive loss of neurons and
intricate interactions between different cell types within the affected regions. Reliable …

[HTML][HTML] Characterization and biomarker analyses of post-COVID-19 complications and neurological manifestations

B Sun, N Tang, MJ Peluso, NS Iyer, L Torres… - Cells, 2021 - mdpi.com
As the SARS-CoV-2 pandemic continues, reports have demonstrated neurologic sequelae
following COVID-19 recovery. Mechanisms to explain long-term neurological sequelae are …

Plant exosomes as novel nanoplatforms for microRNA transfer stimulate neural differentiation of stem cells in vitro and in vivo

XH Xu, TJ Yuan, HA Dad, MY Shi, YY Huang… - Nano …, 2021 - ACS Publications
Differentiation of bone marrow derived mesenchymal stem cells (BMSCs) into functional
neural cells has been widely investigated for treating neural diseases. However, the limited …

[HTML][HTML] A shared, stochastic pathway mediates exosome protein budding along plasma and endosome membranes

FK Fordjour, C Guo, Y Ai, GG Daaboul… - Journal of Biological …, 2022 - ASBMB
Exosomes are small extracellular vesicles of∼ 30 to 150 nm that are secreted by all cells,
abundant in all biofluids, and play important roles in health and disease. However, details …

[HTML][HTML] The evolving landscape of exosomes in neurodegenerative diseases: exosomes characteristics and a promising role in early diagnosis

S Rastogi, V Sharma, PS Bharti, K Rani… - International journal of …, 2021 - mdpi.com
Neurodegenerative diseases (ND) remains to be one of the biggest burdens on healthcare
systems and serves as a leading cause of disability and death. Alzheimer's disease (AD) is …

Scaffolds with controlled release of pro-mineralization exosomes to promote craniofacial bone healing without cell transplantation

WB Swanson, Z Zhang, K Xiu, T Gong, M Eberle… - Acta Biomaterialia, 2020 - Elsevier
Biomimetic bone regeneration methods which demonstrate both clinical and manufacturing
feasibility, as alternatives to autogenic or allogenic bone grafting, remain a challenge to the …

Extracellular vesicles as next generation immunotherapeutics

DW Greening, R Xu, A Ale, CE Hagemeyer… - Seminars in Cancer …, 2023 - Elsevier
Extracellular vesicles (EVs) function as a mode of intercellular communication and
molecular transfer to elicit diverse biological/functional response. Accumulating evidence …

[HTML][HTML] Neural stem cell-derived exosomes and regeneration: cell-free therapeutic strategies for traumatic brain injury

L Zhong, J Wang, P Wang, X Liu, P Liu… - Stem Cell Research & …, 2023 - Springer
Regenerative repair of the brain after traumatic brain injury (TBI) remains an extensive
clinical challenge, inspiring intensified interest in therapeutic approaches to explore superior …

The emerging role of exosomes in Alzheimer's disease

T Zhang, S Ma, J Lv, X Wang, HK Afewerky, H Li… - Ageing research …, 2021 - Elsevier
Abstract Alzheimer's disease (AD), manifested by memory loss and a decline in cognitive
functions, is the most prevalent neurodegenerative disease accounting for 60–80% of …