Improved hygiene leading to reduced exposure to microorganisms has been implicated as
one possible cause for the recent “epidemic” of chronic inflammatory diseases (CIDs) in …

Introduction: The gastrointestinal mucosa constitutes a critical barrier where millions of
microbes and environmental antigens come in close contact with the host immune system …

Background Alteration of the gut microbiota may contribute to the development of
inflammatory bowel disease (IBD). Epigallocatechin-3-gallate (EGCG), a major bioactive …

Background Coffee can regulate glucose homeostasis but the underlying mechanism is
unclear. This study investigated the preventive and therapeutic effects of chlorogenic acid …

Kaempferol, a flavonoid identified in a wide variety of dietary sources, has been reported to
possess anti-obesity properties; however, its underlying mechanism was poorly understood …

Obesity is a global health problem that affects all age groups in both developing and
developed countries. In recent years, the prevalence of overweight and obesity has reached …

Background Little is known about the inter-relationship among fruit and vegetable intake, gut
microbiota and metabolites, and type 2 diabetes (T2D) in human prospective cohort study …

Type 2 diabetes mellitus (T2DM) is characterised by chronic low-grade inflammation,
recently referred to as 'metaflammation', a relevant factor contributing to the development of …

In recent years, research on the interaction between flavonoids and intestinal microbes have
prompted a rash of food science, nutriology and biomedicine, complying with future research …

Background The gut is implicated in the pathogenesis of acute pancreatitis (AP) and the
infectious complications of AP are commonly associated with enteric bacteria, yet whether …