Outer membrane protein A (OmpA) as a potential therapeutic target for Acinetobacter baumannii infection

D Nie, Y Hu, Z Chen, M Li, Z Hou, X Luo, X Mao… - Journal of biomedical …, 2020 - Springer
Acinetobacter baumannii (A. baumannii) is an important opportunistic pathogen causing
serious nosocomial infections, which is considered as the most threatening Gram-negative …

The Outer Membrane Proteins OmpA, CarO, and OprD of Acinetobacter baumannii Confer a Two-Pronged Defense in Facilitating Its Success as a Potent Human …

SR Uppalapati, A Sett, R Pathania - Frontiers in microbiology, 2020 - frontiersin.org
Of all the ESKAPE pathogens, carbapenem-resistant and multidrug-resistant Acinetobacter
baumannii is the leading cause of hospital-acquired and ventilator-associated pneumonia …

Mapping Global Prevalence of Acinetobacter baumannii and Recent Vaccine Development to Tackle It

C Ma, S McClean - Vaccines, 2021 - mdpi.com
Acinetobacter baumannii is a leading cause of nosocomial infections that severely threaten
public health. The formidable adaptability and resistance of this opportunistic pathogen have …

Antimicrobial peptides as a promising treatment option against Acinetobacter baumannii infections

A Neshani, H Sedighian, SA Mirhosseini… - Microbial …, 2020 - Elsevier
Background With the increasing rate of antibiotic resistance in Acinetobacter, the World
Health Organization introduced the carbapenem-resistant isolates in the priority pathogens …

Vaccine development to control the rising scourge of antibiotic-resistant Acinetobacter baumannii: a systematic review

R Singh, N Capalash, P Sharma - 3 Biotech, 2022 - Springer
Acinetobacter baumannii has emerged as one of major nosocomial pathogen and global
emergence of multidrug-resistant strains has become a challenge for developing effective …

Specific egg yolk immunoglobulin as a promising non-antibiotic biotherapeutic product against Acinetobacter baumannii pneumonia infection

A Jahangiri, P Owlia, I Rasooli, J Salimian… - Scientific reports, 2021 - nature.com
Acinetobacter baumannii is a serious health threat with a high mortality rate. We have
already reported prophylactic effects of IgYs raised against OmpA and Omp34 as well as …

BauA and Omp34 surface loops trigger protective antibodies against Acinetobacter baumannii in a murine sepsis model

Z Akbari, I Rasooli, MH Ghaini, S Chaudhuri… - International …, 2022 - Elsevier
The complexity of treating Acinetobacter baumannii infections with the newly developed
resistant strains has led researchers to confront this pathogen by developing vaccines. In …

[HTML][HTML] Reverse vaccinology approach for the identifications of potential vaccine candidates against Salmonella

J Li, J Qiu, Z Huang, T Liu, J Pan, Q Zhang… - International Journal of …, 2021 - Elsevier
Salmonella is a leading cause of foodborne pathogen which causes intestinal and systemic
diseases across the world. Vaccination is the most effective protection against Salmonella …

Outer Membrane Protein, Oma87 Prevents Acinetobacter baumannii Infection

I Rasooli, R Abdolhamidi, A Jahangiri… - International journal of …, 2020 - Springer
Acinetobacter baumannii is one of the most problematic pathogens in clinical settings.
Emerging of its antibiotic-resistant strains persuade researchers to find alternative treatment …

Combination of BauA and OmpA elicit immunoprotection against Acinetobacter baumannii in a murine sepsis model

M Tamehri, I Rasooli, M Pishgahi, A Jahangiri… - Microbial …, 2022 - Elsevier
Aims Acinetobacter baumannii causes severe nosocomial infections and is a difficult-to-treat
pathogen due to the development of multidrug-resistant (MDR) strains. Vaccines and …