The mammalian permanent kidney consists of three cell lineages of different origin: the
epithelial cells of the ureter bud, the mesenchymal cells of the nephric blastema and the …

Tooth development involves complex morphogenetic movements of mesenchymal and
epithelial cells, followed by differentiation of tooth-specific secretory cells. These cells, the …

Summary in humans, germiine mutations of the WT-7 tumor suppressor gene are associated
with both Wiims' tumors and urogenital malformations. To develop a model system for the …

This description of a model system for cell differentiation and organogenesis is written by
one of the foremost researchers in the area. The main emphasis is on the mammalian …

Bone morphogenetic proteins (BMPs) are multifunctional growth factors originally identified
by their ability to induce ectopic bone formation. To investigate the function of one of the …

Growth factor-mediated signaling has been implicated in the regulation of epithelial-
mesenchymal interactions during organogenesls. Bone morphogenetic protein 4 (BMP-4), a …

Corneal endothelial cells maintained in tissue culture retain the ability to synthesize and
secrete an extracellular matrix (ECM) along their basal cell surface. Treatment of confluent …

Development of the metanephric kidney requires the concerted interaction of two tissues, the
epithelium of the ureteric duct and the metanephric mesenchyme. Signals from the ureter …

Growth factors of the transforming growth factor-β (TGF-β) family inhibit the proliferation of
epithelial, endothelial, and hematopoietic cells, and stimulate the synthesis of extracellular …

Regression of the Mullerian duct in the male rat embryo is accompanied by degeneration
and phagocytosis of epithelial and mesenchymal cells, removal of the ductal basement …