Physiology, signaling, and pharmacology of galanin peptides and receptors: three decades of emerging diversity

R Lang, AL Gundlach, FE Holmes, SA Hobson… - Pharmacological …, 2015 - ASPET
Galanin was first identified 30 years ago as a" classic neuropeptide," with actions primarily
as a modulator of neurotransmission in the brain and peripheral nervous system. Other …

Cholinergic system during the progression of Alzheimer's disease: therapeutic implications

EJ Mufson, SE Counts, SE Perez… - Expert review of …, 2008 - Taylor & Francis
Alzheimer's disease (AD) is characterized by a progressive phenotypic downregulation of
markers within cholinergic basal forebrain (CBF) neurons, frank CBF cell loss and reduced …

[HTML][HTML] Progress report on new antiepileptic drugs: a summary of the Eleventh Eilat Conference (EILAT XI)

M Bialer, SI Johannessen, RH Levy, E Perucca… - Epilepsy research, 2013 - Elsevier
The Eleventh Eilat Conference on New Antiepileptic Drugs (AEDs)-EILAT XI, took place in
Eilat, Israel from the 6th to 10th of May 2012. About 100 basic scientists, clinical …

The galanin peptide family: receptor pharmacology, pleiotropic biological actions, and implications in health and disease

R Lang, AL Gundlach, B Kofler - Pharmacology & therapeutics, 2007 - Elsevier
The galanin peptide family consists of the “parental” galanin, galanin-message-associated
peptide (GMAP) which derives from the same peptide precursor gene product as galanin …

[HTML][HTML] Galanin receptors and ligands

KEB Webling, J Runesson, T Bartfai… - Frontiers in …, 2012 - frontiersin.org
The neuropeptide galanin was first discovered 30 years ago. Today, the galanin family
consists of galanin, galanin-like peptide (GALP), galanin-message associated peptide …

The making of successful axonal regeneration: genes, molecules and signal transduction pathways

G Raivich, M Makwana - Brain research reviews, 2007 - Elsevier
Unlike its central counterpart, the peripheral nervous system is well known for its
comparatively good potential for regeneration following nerve fiber injury. This ability is …

Galanin acts as a neuroprotective factor to the hippocampus

CR Elliott-Hunt, B Marsh, A Bacon… - Proceedings of the …, 2004 - National Acad Sciences
The expression of the neuropeptide galanin is markedly up-regulated in many areas of the
central and peripheral nervous system after injury. We have recently demonstrated that …

Activation of the galanin receptor 2 (GalR2) protects the hippocampus from neuronal damage

CR Elliott‐Hunt, RJP Pope… - Journal of …, 2007 - Wiley Online Library
Expression of the neuropeptide galanin is up‐regulated in many brain regions following
nerve injury and in the basal forebrain of patients with Alzheimer's disease. We have …

Cardiac innervation in acute myocardial ischaemia/reperfusion injury and cardioprotection

DJ Hausenloy, HE Bøtker, P Ferdinandy… - Cardiovascular …, 2019 - academic.oup.com
Acute myocardial infarction (AMI) and the heart failure (HF) that often complicates this
condition, are among the leading causes of death and disability worldwide. To reduce …

Galanin and its receptors in neurological disorders

L Lundström, A Elmquist, T Bartfai, Ü Langel - Neuromolecular medicine, 2005 - Springer
Galanin is a highly inducible neuropeptide, showing distinct up-regulation after pathological
disturbance within the nervous system. Significant increase in galanin expression is …