Bruton's tyrosine kinase (BTK) is a non-receptor kinase that plays a crucial role in oncogenic
signaling that is critical for proliferation and survival of leukemic cells in many B cell …

Chronic GVHD, an autoimmune disease that follows allogeneic hematopoietic-cell
transplantation, is characterized by infections and debilitating tissue injury leading to …

Post-Transplantation Lymphoproliferative Disorders Solid-organ and hematopoietic stem-
cell transplants are widely used for various life-threatening medical disorders. Prophylaxis …

Opportunistic infections caused by Pneumocystis jirovecii, Cryptococcus neoformans, and
ubiquitous airborne filamentous fungi have been recently reported in patients with …

Bruton's tyrosine kinase (BTK) has emerged as a promising drug target for multiple
diseases, particularly haematopoietic malignancies and autoimmune diseases related to B …

Chronic graft-versus-host disease (cGvHD) is a severe complication of allogeneic
hematopoietic stem cell transplantation that affects various organs leading to a reduced …

Graft-versus-host disease (GVHD) is an immunological reaction and a frequent complication
following allogeneic hematopoietic stem cell transplantation. It is associated with high …

Chronic graft-versus-host disease (cGVHD) is a major immunologic complication of
allogeneic hematopoietic cell transplantation. cGVHD involves multiple organs, reduces …

Graft versus host disease (GVHD) remains a major cause of morbidity and mortality
following allogeneic hematopoietic stem-cell transplantation (HSCT). Despite the use of …

The use of Bruton's tyrosine kinase (BTK) inhibitors has changed the management of
patients with B-cell lymphoid malignancies. BTK is an important molecule that interconnects …