Role of Bruton's tyrosine kinase in B cells and malignancies
S Pal Singh, F Dammeijer, RW Hendriks - Molecular cancer, 2018 - Springer
Bruton's tyrosine kinase (BTK) is a non-receptor kinase that plays a crucial role in oncogenic
signaling that is critical for proliferation and survival of leukemic cells in many B cell …
signaling that is critical for proliferation and survival of leukemic cells in many B cell …
Pathophysiology of chronic graft-versus-host disease and therapeutic targets
Chronic GVHD, an autoimmune disease that follows allogeneic hematopoietic-cell
transplantation, is characterized by infections and debilitating tissue injury leading to …
transplantation, is characterized by infections and debilitating tissue injury leading to …
Post-transplantation lymphoproliferative disorders in adults
D Dierickx, TM Habermann - New England Journal of Medicine, 2018 - Mass Medical Soc
Post-Transplantation Lymphoproliferative Disorders Solid-organ and hematopoietic stem-
cell transplants are widely used for various life-threatening medical disorders. Prophylaxis …
cell transplants are widely used for various life-threatening medical disorders. Prophylaxis …
Call for action: invasive fungal infections associated with ibrutinib and other small molecule kinase inhibitors targeting immune signaling pathways
G Chamilos, MS Lionakis… - Clinical Infectious …, 2018 - academic.oup.com
Opportunistic infections caused by Pneumocystis jirovecii, Cryptococcus neoformans, and
ubiquitous airborne filamentous fungi have been recently reported in patients with …
ubiquitous airborne filamentous fungi have been recently reported in patients with …
The development of Bruton's tyrosine kinase (BTK) inhibitors from 2012 to 2017: A mini-review
C Liang, D Tian, X Ren, S Ding, M Jia, M Xin… - European journal of …, 2018 - Elsevier
Bruton's tyrosine kinase (BTK) has emerged as a promising drug target for multiple
diseases, particularly haematopoietic malignancies and autoimmune diseases related to B …
diseases, particularly haematopoietic malignancies and autoimmune diseases related to B …
New approaches for the treatment of chronic graft-versus-host disease: current status and future directions
Chronic graft-versus-host disease (cGvHD) is a severe complication of allogeneic
hematopoietic stem cell transplantation that affects various organs leading to a reduced …
hematopoietic stem cell transplantation that affects various organs leading to a reduced …
Cutaneous graft-versus-host disease: diagnosis and treatment
K Strong Rodrigues, C Oliveira-Ribeiro… - American journal of …, 2018 - Springer
Graft-versus-host disease (GVHD) is an immunological reaction and a frequent complication
following allogeneic hematopoietic stem cell transplantation. It is associated with high …
following allogeneic hematopoietic stem cell transplantation. It is associated with high …
Three US Food and Drug Administration–approved therapies for chronic GVHD
R Zeiser, SJ Lee - Blood, The Journal of the American Society …, 2022 - ashpublications.org
Chronic graft-versus-host disease (cGVHD) is a major immunologic complication of
allogeneic hematopoietic cell transplantation. cGVHD involves multiple organs, reduces …
allogeneic hematopoietic cell transplantation. cGVHD involves multiple organs, reduces …
New and emerging therapies for acute and chronic graft versus host disease
LQ Hill, A Alousi, P Kebriaei, R Mehta… - Therapeutic …, 2018 - journals.sagepub.com
Graft versus host disease (GVHD) remains a major cause of morbidity and mortality
following allogeneic hematopoietic stem-cell transplantation (HSCT). Despite the use of …
following allogeneic hematopoietic stem-cell transplantation (HSCT). Despite the use of …
Bruton's kinase inhibitors for the treatment of immunological diseases: current status and perspectives
E Robak, T Robak - Journal of Clinical Medicine, 2022 - mdpi.com
The use of Bruton's tyrosine kinase (BTK) inhibitors has changed the management of
patients with B-cell lymphoid malignancies. BTK is an important molecule that interconnects …
patients with B-cell lymphoid malignancies. BTK is an important molecule that interconnects …