Synthesis of glycoproteins

BG Davis - Chemical reviews, 2002 - ACS Publications
It is becoming ever clearer that the presence of carbohydrate units in naturally occurring
structures and their mimetics has a dramatic effect on their physical, chemical, and biological …

A decade of glycodendrimer chemistry

R Roy - Trends in Glycoscience and Glycotechnology, 2003 - jstage.jst.go.jp
抄録 グリコデンドリマー研究の最近 10 年は, グリコデンドリマーのデザインと生物学的応用の両方
の点で, 非常に大きく洗練されてきたことが証明されている. これらの人工的な多分岐糖鎖の中には …

Advances in bioconjugation

J Kalia, RT Raines - Current organic chemistry, 2010 - ingentaconnect.com
Bioconjugation is a burgeoning field of research. Novel methods for the mild and site-
specific derivatization of proteins, DNA, RNA, and carbohydrates have been developed for …

Mannodendrimers prevent acute lung inflammation by inhibiting neutrophil recruitment

E Blattes, A Vercellone, H Eutamène… - Proceedings of the …, 2013 - National Acad Sciences
Mycobacterium tuberculosis mannose-capped lipoarabinomannan inhibits the release of
proinflammatory cytokines by LPS-stimulated human dendritic cells (DCs) via targeting the C …

Dendritic catalysts

R Kreiter, AW Kleij, RJMK Gebbink… - Dendrimers IV: metal …, 2001 - Springer
After the publication of the first papers on dendritic catalysts in 1994, many different
examples in this class of (macro) molecular catalysts have been reported in recent years …

Glycodendrimers

N Röckendorf, TK Lindhorst - Dendrimers IV: Metal Coordination, Self …, 2001 - Springer
Glycodendrimers have become valuable tools in glycobiology especially in the context of
multivalency which is an important principle of carbohydrate-protein interactions …

α-Oxo aldehyde or glyoxylyl group chemistry in peptide bioconjugation

O El-Mahdi, O Melnyk - Bioconjugate chemistry, 2013 - ACS Publications
Since the 1990s, α-oxo aldehyde or glyoxylic acid chemistry has inspired a vast array of
synthetic tools for tailoring peptide or protein structures, for developing peptides endowed …

Chemoselective assembly and immunological evaluation of multiepitopic glycoconjugates bearing clustered Tn antigen as synthetic anticancer vaccines

S Grigalevicius, S Chierici, O Renaudet… - Bioconjugate …, 2005 - ACS Publications
In this paper we investigated the use of regioselectively addressable functionalized
templates (RAFTs) as new scaffolds for the design of anticancer vaccine candidates. We …

Clustered carbohydrates in synthetic vaccines

F Peri - Chemical Society Reviews, 2013 - pubs.rsc.org
Are there general rules to obtain efficient immunization against carbohydrate antigens?
Thanks to technological advances in glycobiology and glycochemistry we entered a new era …

Glycodendritic Structures Based on Boltorn Hyperbranched Polymers and Their Interactions with Lens culinaris Lectin

E Arce, PM Nieto, V Díaz, RG Castro… - Bioconjugate …, 2003 - ACS Publications
Multivalent scaffolds bearing carbohydrates have been prepared to mediate biological
processes where carbohydrates are involved. These systems consist of dendritic structures …