Uncovering the mechanisms of virus infection and assembly is crucial for preventing the
spread of viruses and treating viral disease. The technique of single-virus tracking (SVT) …

Viruses and other selfish genetic elements are dominant entities in the biosphere, with
respect to both physical abundance and genetic diversity. Various selfish elements …

Many biological membranes are asymmetric and exhibit complex lipid composition,
comprising hundreds of distinct chemical species. Identifying the biological function and …

In flowering plants, pollen tubes undergo tip growth to deliver two nonmotile sperm to the
ovule where they fuse with an egg and central cell to achieve double fertilization. This …

HIV-1 entry into CD4+ target cells is mediated by cleaved envelope glycoprotein (Env)
trimers that have been challenging to characterize structurally. Here, we describe the crystal …

Interferons (IFN) are essential antiviral cytokines that establish the cellular antiviral state
through upregulation of hundreds of interferon-stimulated genes (ISGs), most of which have …

The cell imposes multiple barriers to virus entry. However, viruses exploit fundamental
cellular processes to gain entry to cells and deliver their genetic cargo. Virus entry pathways …

Chikungunya virus (CHIKV) is an emerging mosquito-borne alphavirus that has caused
widespread outbreaks of debilitating human disease in the past five years. CHIKV invasion …

Regulated by pH, membrane-anchored proteins E and M function during dengue virus
maturation and membrane fusion. Our atomic model of the whole virion from cryo–electron …

Hepatitis C virus, a major human pathogen, produces infectious virus particles with several
unique features, such as an ability to interact with serum lipoproteins, a dizzyingly …