Bone disease and skeletal complications in patients with β thalassemia major

R Haidar, KM Musallam, AT Taher - Bone, 2011 - Elsevier
Increased survival in patients with β thalassemia major (TM) allowed for several
complications of the disease and its treatment to manifest, one of which is bone disease …

Thalassemia-associated osteoporosis: a systematic review on treatment and brief overview of the disease

AD Dede, G Trovas, E Chronopoulos… - Osteoporosis …, 2016 - Springer
Thalassemia-associated osteoporosis constitutes a major complication in patients with
thalassemia. This review presents the existing studies on the treatment of thalassemia …

Effect of enhanced iron chelation therapy on glucose metabolism in patients with β‐thalassaemia major

K Farmaki, N Angelopoulos… - British journal of …, 2006 - Wiley Online Library
Recently introduced chelation regimens that combine deferoxamine (DFO) and deferiprone
have been shown to have greater efficacy in promoting iron excretion than either chelator …

Augmentation of cortical bone mineral density in women with polycystic ovary syndrome: a peripheral quantitative computed tomography (pQCT) study

D Kassanos, E Trakakis, CS Baltas… - Human …, 2010 - academic.oup.com
BACKGROUND Women with polycystic ovary syndrome (PCOS) may have increased
cortical bone mineral density (BMD) and probably higher bone material quality as well as …

The spine in β-thalassemia syndromes

R Haidar, H Mhaidli, KM Musallam, AT Taher - Spine, 2012 - journals.lww.com
Study Design. Literature review. Objective. To present a comprehensive overview of spinal
involvement in patients with β-thalassemia, aiming to orient the spinal surgeon to these …

Bone demineralization in adult thalassaemic patients: contribution of GH and IGF‐I at different skeletal sites

M Scacchi, L Danesi, A Cattaneo, E Valassi… - Clinical …, 2008 - Wiley Online Library
Background and objective GH and IGF‐I exert an important role in the control of bone
formation, as shown by decreased bone mineral density and increased fracture risk in adult …

Prevalence of osteoporosis among thalassemia patients from Zafar adult thalassemia clinic, Iran

M Hashemieh, A Azarkeivan, M Radfar… - Iranian Journal of Blood …, 2014 - ijbc.ir
Background: The advances in treatment regimes for thalassemic patients have increased
the survival among them therefore osteoporosis has emerged as an important cause of …

The role of opportunistic quantitative computed tomography in the evaluation of bone disease and risk of fracture in thalassemia major

A Carnevale, F Pellegrino, B Bravi… - European Journal of …, 2022 - Wiley Online Library
Objective Dual‐energy X‐ray absorptiometry (DXA) remains the cornerstone for
osteoporosis evaluation in Thalassemia major. However, several drawbacks have been …

Bone status and HCV infection in thalassemia major patients

A Meloni, L Pistoia, S Maffei, P Ricchi, T Casini… - Bone, 2023 - Elsevier
Abstract Purpose Hepatitis C virus (HCV) infection increases the risk for osteoporosis but
this relationship has not been investigated among multi-transfused patients with thalassemia …

Bone turnover, areal BMD and bone microarchitecture by second-generation high-resolution peripheral quantitative tomography in transfusion-dependent …

L Das, A Khadwal, P Malhotra, J Ghosh, V Dhiman… - JBMR Plus, 2024 - academic.oup.com
Thalassemic osteopathy includes low bone mass and impaired bone microarchitecture. We
aimed to evaluate the prevalence and determinants of bone quantity (osteoporosis) and …