Down syndrome
Trisomy 21, the presence of a supernumerary chromosome 21, results in a collection of
clinical features commonly known as Down syndrome (DS). DS is among the most …
clinical features commonly known as Down syndrome (DS). DS is among the most …
Longitudinal neuroanatomical and behavioral analyses show phenotypic drift and variability in the Ts65Dn mouse model of Down syndrome
PR Shaw, JA Klein, NM Aziz… - Disease models & …, 2020 - journals.biologists.com
Mouse models of Down syndrome (DS) have been invaluable tools for advancing
knowledge of the underlying mechanisms of intellectual disability in people with DS. The Ts …
knowledge of the underlying mechanisms of intellectual disability in people with DS. The Ts …
Behavioral phenotyping for Down syndrome in mice
RJ Roper, CR Goodlett… - Current protocols in …, 2020 - Wiley Online Library
Down syndrome (DS) is the most frequent genetic cause of intellectual disability,
characterized by alterations in different behavioral symptom domains: neurodevelopment …
characterized by alterations in different behavioral symptom domains: neurodevelopment …
Identifying phenotypic change across time in mouse models of Down syndrome
PR Shaw - 2021 - search.proquest.com
Advances in Down syndrome (DS) research depend on the availability of mouse models that
replicate the genetic landscape and resulting phenotypes of DS which allow for …
replicate the genetic landscape and resulting phenotypes of DS which allow for …
Functional Assessment of Human 21st Chromosome Orthologs in Caenorhabditis elegans
S Smith - 2020 - repositories.lib.utexas.edu
Down syndrome (DS) is a neurodevelopmental disorder caused by having an extra copy of
the 21st chromosome. Every person with DS exhibits muscle weakness and ID, though the …
the 21st chromosome. Every person with DS exhibits muscle weakness and ID, though the …