The diversification of methods for studying cell–cell interactions and communication
No cell lives in a vacuum, and the molecular interactions between cells define most
phenotypes. Transcriptomics provides rich information to infer cell–cell interactions and …
phenotypes. Transcriptomics provides rich information to infer cell–cell interactions and …
Cell–cell communication: new insights and clinical implications
J Su, Y Song, Z Zhu, X Huang, J Fan, J Qiao… - Signal Transduction and …, 2024 - nature.com
Multicellular organisms are composed of diverse cell types that must coordinate their
behaviors through communication. Cell–cell communication (CCC) is essential for growth …
behaviors through communication. Cell–cell communication (CCC) is essential for growth …
Comparison of methods and resources for cell-cell communication inference from single-cell RNA-Seq data
The growing availability of single-cell data, especially transcriptomics, has sparked an
increased interest in the inference of cell-cell communication. Many computational tools …
increased interest in the inference of cell-cell communication. Many computational tools …
Screening cell–cell communication in spatial transcriptomics via collective optimal transport
Spatial transcriptomic technologies and spatially annotated single-cell RNA sequencing
datasets provide unprecedented opportunities to dissect cell–cell communication (CCC) …
datasets provide unprecedented opportunities to dissect cell–cell communication (CCC) …
High-resolution single-cell atlas reveals diversity and plasticity of tissue-resident neutrophils in non-small cell lung cancer
Non-small cell lung cancer (NSCLC) is characterized by molecular heterogeneity with
diverse immune cell infiltration patterns, which has been linked to therapy sensitivity and …
diverse immune cell infiltration patterns, which has been linked to therapy sensitivity and …
Squidpy: a scalable framework for spatial omics analysis
Spatial omics data are advancing the study of tissue organization and cellular
communication at an unprecedented scale. Flexible tools are required to store, integrate and …
communication at an unprecedented scale. Flexible tools are required to store, integrate and …
[HTML][HTML] Spatial multi-omic map of human myocardial infarction
Myocardial infarction is a leading cause of death worldwide. Although advances have been
made in acute treatment, an incomplete understanding of remodelling processes has limited …
made in acute treatment, an incomplete understanding of remodelling processes has limited …
decoupleR: ensemble of computational methods to infer biological activities from omics data
P Badia-i-Mompel, J Vélez Santiago… - Bioinformatics …, 2022 - academic.oup.com
Many methods allow us to extract biological activities from omics data using information from
prior knowledge resources, reducing the dimensionality for increased statistical power and …
prior knowledge resources, reducing the dimensionality for increased statistical power and …
[HTML][HTML] Fibrin drives thromboinflammation and neuropathology in COVID-19
Life-threatening thrombotic events and neurological symptoms are prevalent in COVID-19
and are persistent in patients with long COVID experiencing post-acute sequelae of SARS …
and are persistent in patients with long COVID experiencing post-acute sequelae of SARS …
CellCall: integrating paired ligand–receptor and transcription factor activities for cell–cell communication
Y Zhang, T Liu, X Hu, M Wang, J Wang… - Nucleic acids …, 2021 - academic.oup.com
With the dramatic development of single-cell RNA sequencing (scRNA-seq) technologies,
the systematic decoding of cell-cell communication has received great research interest. To …
the systematic decoding of cell-cell communication has received great research interest. To …