Sarcopenia: aging-related loss of muscle mass and function
Sarcopenia is a loss of muscle mass and function in the elderly that reduces mobility,
diminishes quality of life, and can lead to fall-related injuries, which require costly …
diminishes quality of life, and can lead to fall-related injuries, which require costly …
Fibronectin: molecular structure, fibrillar structure and mechanochemical signaling
CJ Dalton, CA Lemmon - Cells, 2021 - mdpi.com
The extracellular matrix (ECM) plays a key role as both structural scaffold and regulator of
cell signal transduction in tissues. In times of ECM assembly and turnover, cells upregulate …
cell signal transduction in tissues. In times of ECM assembly and turnover, cells upregulate …
Programmably controllable delivery of metastable ferrous ions for multiscale dynamic imaging guided photothermal primed chemodynamic therapy
X Zhang, S Lin, F Zhao, J Zhang, S Lei, F Bai… - Advanced …, 2023 - Wiley Online Library
Metallomodulation cell death strategies are extensively investigated for antitumor therapy,
such as cuproptosis, ferroptosis, and chemodynamic therapy (CDT). Undoubtedly, the …
such as cuproptosis, ferroptosis, and chemodynamic therapy (CDT). Undoubtedly, the …
Mavacamten, a precision medicine for hypertrophic cardiomyopathy: From a motor protein to patients
Hypertrophic cardiomyopathy (HCM) is a primary myocardial disorder characterized by left
ventricular hypertrophy, hyperdynamic contraction, and impaired relaxation of the heart …
ventricular hypertrophy, hyperdynamic contraction, and impaired relaxation of the heart …
Active matter at the interface between materials science and cell biology
D Needleman, Z Dogic - Nature reviews materials, 2017 - nature.com
The remarkable processes that characterize living organisms, such as motility, self-healing
and reproduction, are fuelled by a continuous injection of energy at the microscale. The field …
and reproduction, are fuelled by a continuous injection of energy at the microscale. The field …
Hydrodynamics of soft active matter
This review summarizes theoretical progress in the field of active matter, placing it in the
context of recent experiments. This approach offers a unified framework for the mechanical …
context of recent experiments. This approach offers a unified framework for the mechanical …
Direct observation of kinesin stepping by optical trapping interferometry
Do biological motors move with regular steps? To address this question, we constructed
instrumentation with the spatial and temporal sensitivity to resolve movement on a molecular …
instrumentation with the spatial and temporal sensitivity to resolve movement on a molecular …
Single myosin molecule mechanics: piconewton forces and nanometre steps
JT Finer, RM Simmons, JA Spudich - Nature, 1994 - nature.com
A new in vitro assay using a feedback enhanced laser trap system allows direct
measurement of force and displacement that results from the interaction of a single myosin …
measurement of force and displacement that results from the interaction of a single myosin …
Synthetic molecular motors and mechanical machines
The widespread use of controlled molecular‐level motion in key natural processes suggests
that great rewards could come from bridging the gap between the present generation of …
that great rewards could come from bridging the gap between the present generation of …
Modeling molecular motors
The authors present general considerations and simple models for the operation of
isothermal motors at small scales, in asymmetric environments. Their work is inspired by …
isothermal motors at small scales, in asymmetric environments. Their work is inspired by …