In recent years, claims of increased involvement of non–cytochrome P450 (non-P450)
enzymes in the metabolism of drugs have appeared in the literature. However, no temporal …

Abstract Human carboxylesterase 1 (CES1) and carboxylesterase 2 (CES2) are serine
esterases responsible for the hydrolysis of ester and amide bonds present in a number of …

This work provides an elaborate characterization of human intestinal fluids (HIF) collected in
fasted-and fed-state conditions. HIF from 20 healthy volunteers (10 M/F) were aspirated by …

Abstract Carboxylesterase 2 (CES2) is a serine-type hydrolase that plays important roles in
xenobiotic detoxification and lipid metabolism. Its abnormal expression is highly associated …

In almost 30 years since the introduction of HMG-CoA reductase inhibitors (statins), no other
class of lipid modulators has entered the market. Elevation of high-density lipoprotein …

Thermally activated delayed fluorescence (TADF) materials with long-lived fluorescent
emission, have been considered to be promising candidates for time-resolved luminescence …

Carboxylesterases (CESs) are critical for metabolizing ester-containing biomolecules and
are specifically important in liver metabolic disorders. The modulation of CESs is also an …

A novel hydrosoluble near-infrared fluorescence off–on probe has been developed for
detecting carboxylesterase activity. The probe was designed by introducing (4 …

Carboxylesterases (CEs) are widely distributed enzymes in the human body that catalyze
hydrolysis of various endogenous and exogenous substrates. They are directly linked to …

Pyrethroids are broad-spectrum insecticides that widely used in many countries, while
humans may be exposed to these toxins by drinking or eating pesticide-contaminated foods …