Heteronuclear multidimensional NMR experiments for the structure determination of proteins in solution employing pulsed field gradients
M Sattler, J Schleucher, C Griesinger - Progress in nuclear magnetic …, 1999 - Elsevier
6. 3D and 4D NOESY/ROESY experiments............................................ 146 6.1. 13C-and 15N-
edited NOESY/ROESY experiments.................................. 146 6.2. Filtered experiments for …
edited NOESY/ROESY experiments.................................. 146 6.2. Filtered experiments for …
Nuclear magnetic resonance methods for quantifying microsecond-to-millisecond motions in biological macromolecules
AG Palmer III, CD Kroenke, JP Loria - Methods in enzymology, 2001 - Elsevier
Protein function depends on transitions from the ground state to higher energy states.
Deviations from the ground-state structure result from chemical reactivity and conformational …
Deviations from the ground-state structure result from chemical reactivity and conformational …
HSP40 proteins use class-specific regulation to drive HSP70 functional diversity
O Faust, M Abayev-Avraham, AS Wentink, M Maurer… - Nature, 2020 - nature.com
The ubiquitous heat shock protein 70 (HSP70) family consists of ATP-dependent molecular
chaperones, which perform numerous cellular functions that affect almost all aspects of the …
chaperones, which perform numerous cellular functions that affect almost all aspects of the …
Structure and ligand of a histone acetyltransferase bromodomain
C Dhalluin, JE Carlson, L Zeng, C He, AK Aggarwal… - Nature, 1999 - nature.com
Histone acetylation is important in chromatin remodelling and gene activation,,,. Nearly all
known histone-acetyltransferase (HAT)-associated transcriptional co-activators contain …
known histone-acetyltransferase (HAT)-associated transcriptional co-activators contain …
Autoinhibition and activation mechanisms of the Wiskott–Aldrich syndrome protein
AS Kim, LT Kakalis, N Abdul-Manan, GA Liu… - Nature, 2000 - nature.com
Abstract The Rho-family GTPase, Cdc42, can regulate the actin cytoskeleton through
activation of Wiskott–Aldrich syndrome protein (WASP) family members. Activation relieves …
activation of Wiskott–Aldrich syndrome protein (WASP) family members. Activation relieves …
THE USE OF 2H, 13C, 15N MULTIDIMENSIONAL NMR GTO STUDY THE STRUCTURE AND DYNAMICS OF PROTEINS
KH Gardner, LE Kay - Annual review of biophysics and …, 1998 - annualreviews.org
▪ Abstract During the past thirty years, deuterium labeling has been used to improve the
resolution and sensitivity of protein NMR spectra used in a wide variety of applications. Most …
resolution and sensitivity of protein NMR spectra used in a wide variety of applications. Most …
Unraveling the mechanism of protein disaggregation through a ClpB-DnaK interaction
HSP-100 protein machines, such as ClpB, play an essential role in reactivating protein
aggregates that can otherwise be lethal to cells. Although the players involved are known …
aggregates that can otherwise be lethal to cells. Although the players involved are known …
ZATT (ZNF451)–mediated resolution of topoisomerase 2 DNA-protein cross-links
MJ Schellenberg, JA Lieberman, A Herrero-Ruiz… - Science, 2017 - science.org
Topoisomerase 2 (TOP2) DNA transactions proceed via formation of the TOP2 cleavage
complex (TOP2cc), a covalent enzyme-DNA reaction intermediate that is vulnerable to …
complex (TOP2cc), a covalent enzyme-DNA reaction intermediate that is vulnerable to …
Ile, Leu, and Val methyl assignments of the 723-residue malate synthase G using a new labeling strategy and novel NMR methods
V Tugarinov, LE Kay - Journal of the American Chemical Society, 2003 - ACS Publications
New NMR experiments are presented for the assignment of methyl 13C and 1H chemical
shifts from Ile, Leu, and Val residues in high molecular weight proteins. The first class of …
shifts from Ile, Leu, and Val residues in high molecular weight proteins. The first class of …
Structure of the recombinant full-length hamster prion protein PrP (29–231): the N terminus is highly flexible
DG Donne, JH Viles, D Groth… - Proceedings of the …, 1997 - National Acad Sciences
The prion diseases seem to be caused by a conformational change of the prion protein (PrP)
from the benign cellular form PrPC to the infectious scrapie form PrPSc; thus, detailed …
from the benign cellular form PrPC to the infectious scrapie form PrPSc; thus, detailed …