The neurotransmitter dopamine is a key factor in central nervous system (CNS) function,
regulating many processes including reward, movement, and cognition. Dopamine also …

Inflammatory bowel disease (IBD) is a chronic immune-mediated inflammation of the
gastrointestinal tract with a highly heterogeneous presentation. It has a relapsing and …

Mendelian randomisation (MR) analysis is an important tool to elucidate the causal
relevance of environmental and biological risk factors for disease. However, causal …

Mesenchymal stromal cells (MSCs) are currently widely used in cell based therapy
regarding to their remarkable efficacy in controlling the inflammatory status in patients …

The complex pathogenesis of inflammatory bowel disease (IBD) explains the several
hurdles for finding an efficient approach to cure it. Nowadays, therapeutic protocols aim to …

Psoriasis is a chronic, immune-mediated inflammatory disease that affects around 125
million people worldwide. Several studies concerning the gut microbiota composition and its …

Crohn's disease (CD) and ulcerative colitis (UC), known as inflammatory bowel diseases
(IBD), are characterized by chronic inflammation of the gastrointestinal tract. Over the last …

Monoclonal antibodies (mAbs) are immunoglobulins designed to target a specific epitope on
an antigen. Immunoglobulins of identical amino-acid sequence were originally produced by …

Background: Treatment of inflammatory bowel diseases (IBD) has tremendously improved
during the last 20 years; however, a substantial fraction of patients does not respond to …

Abstract Inflammatory Bowel Disease (IBD) are autoimmune diseases characterized by
chronic intestinal inflammation. Considered a western disease, IBD incidence in newly …