Among fungal pathogens, Cryptococcus neoformans has gained great importance among
the scientific community of several reasons. This fungus is the causative agent of …

Deadly infections from opportunistic fungi have risen in frequency, largely because of the at-
risk immunocompromised population created by advances in modern medicine and the …

Cryptococcus neoformans is an opportunistic pathogenic yeast that causes serious
infections, most commonly of the central nervous system (CNS). C. neoformans is mainly …

Alveolar macrophages (AMs) are the major lung-resident macrophages and have
contradictory functions. AMs maintain tolerance and tissue homeostasis, but they also …

Cryptococcus species, the etiological agents of cryptococcosis, are encapsulated fungal
yeasts that predominantly cause disease in immunocompromised individuals, and are …

The plasma membrane (PM) performs a plethora of physiological processes, the
coordination of which requires spatial and temporal organization into specialized domains of …

Nutrient sensing is critical for adaptation of fungi to environmental and host conditions. The
conserved cAMP/PKA signaling pathway contributes to adaptation by sensing the …

Fungi often adapt to environmental stress by altering their size, shape, or rate of cell division.
These morphological changes require reorganization of the cell wall, a structural feature …

Cryptococcus neoformans is a common environmental saprophyte and human fungal
pathogen that primarily causes disease in immunocompromised individuals. Similar to many …

The human fungal pathogen, Cryptococcus neoformans, dramatically alters its cell wall, both
in size and composition, upon entering the host. This cell wall remodeling is essential for …