The antihypertensive potential of flavonoids from Chinese Herbal Medicine: A review
Y Cao, L Xie, K Liu, Y Liang, X Dai, X Wang, J Lu… - Pharmacological …, 2021 - Elsevier
With the coming of the era of the aging population, hypertension has become a global health
burden to be dealt with. Although there are multiple drugs and procedures to control the …
burden to be dealt with. Although there are multiple drugs and procedures to control the …
[HTML][HTML] Nanosuspensions technology as a master key for nature products drug delivery and in vivo fate
Y Ma, Z Cong, P Gao, Y Wang - European Journal of Pharmaceutical …, 2023 - Elsevier
The drug nanosuspensions is a universal formulation approach for improved drug delivery
of hydrophobic drugs and one the most promising approaches for increasing the …
of hydrophobic drugs and one the most promising approaches for increasing the …
[HTML][HTML] Flavonoid production: current trends in plant metabolic engineering and de novo microbial production
Flavonoids are secondary metabolites that represent a heterogeneous family of plant
polyphenolic compounds. Recent research has determined that the health benefits of fruits …
polyphenolic compounds. Recent research has determined that the health benefits of fruits …
The fate of flavonoids after oral administration: A comprehensive overview of its bioavailability
A Naeem, Y Ming, H Pengyi, KY Jie, L Yali… - Critical reviews in …, 2022 - Taylor & Francis
Despite advancements in synthetic chemistry, nature remains the primary source of drug
discovery, and this never-ending task of finding novel and active drug molecules will …
discovery, and this never-ending task of finding novel and active drug molecules will …
Current methodologies to refine bioavailability, delivery, and therapeutic efficacy of plant flavonoids in cancer treatment
CG Vazhappilly, M Amararathna, AC Cyril… - The Journal of …, 2021 - Elsevier
Over the last two decades, several advancements have been made to improve the
therapeutic efficacy of plant flavonoids, especially in cancer treatment. Factors such as low …
therapeutic efficacy of plant flavonoids, especially in cancer treatment. Factors such as low …
Exploring the treatment of COVID‐19 with Yinqiao powder based on network pharmacology
H Lin, X Wang, M Liu, M Huang, Z Shen… - Phytotherapy …, 2021 - Wiley Online Library
Coronavirus disease 2019 (COVID‐19) is caused by severe acute respiratory syndrome
coronavirus 2 (SARS‐CoV‐2). In China, Yinqiao powder is widely used to prevent and treat …
coronavirus 2 (SARS‐CoV‐2). In China, Yinqiao powder is widely used to prevent and treat …
[HTML][HTML] Drug nanocrystals for active tumor-targeted drug delivery
L Lu, Q Xu, J Wang, S Wu, Z Luo, W Lu - Pharmaceutics, 2022 - mdpi.com
Drug nanocrystals, which are comprised of active pharmaceutical ingredients and only a
small amount of essential stabilizers, have the ability to improve the solubility, dissolution …
small amount of essential stabilizers, have the ability to improve the solubility, dissolution …
[HTML][HTML] Rutin nanocrystals with enhanced anti-inflammatory activity: Preparation and ex vivo/in vivo evaluation in an inflammatory rat model
AS Hassan, GM Soliman - Pharmaceutics, 2022 - mdpi.com
Rutin is a polyphenolic flavonoid with an interestingly wide therapeutic spectrum. However,
its clinical benefits are limited by its poor aqueous solubility and low bioavailability. In an …
its clinical benefits are limited by its poor aqueous solubility and low bioavailability. In an …
[HTML][HTML] The contribution of absorption of integral nanocrystals to enhancement of oral bioavailability of quercetin
B Shen, C Shen, W Zhu, H Yuan - Acta Pharmaceutica Sinica B, 2021 - Elsevier
In this study, self-discriminating hybrid nanocrystals was utilized to explore the biological
fate of quercetin hybrid nanocrystals (QT-HNCs) with diameter around 280 nm (QT-HNCs …
fate of quercetin hybrid nanocrystals (QT-HNCs) with diameter around 280 nm (QT-HNCs …
Resveratrol and its nanocrystals: A promising approach for cancer therapy?
There has been a significant research interest in nanocrystals as a promising technology for
improving the therapeutic efficacy of poorly water-soluble drugs, such as resveratrol. Little is …
improving the therapeutic efficacy of poorly water-soluble drugs, such as resveratrol. Little is …