[HTML][HTML] The role of mitochondrial cardiolipin in heart function and its implication in cardiac disease

J Dudek, M Hartmann, P Rehling - … Acta (BBA)-Molecular Basis of Disease, 2019 - Elsevier
Mitochondria play an essential role in the energy metabolism of the heart. Many of the
essential functions are associated with mitochondrial membranes and oxidative …

The role of cardiolipin in cardiovascular health

Z Shen, C Ye, K McCain… - BioMed research …, 2015 - Wiley Online Library
Cardiolipin (CL), the signature phospholipid of mitochondrial membranes, is crucial for both
mitochondrial function and cellular processes outside of the mitochondria. The importance of …

Quantitative lipidomics reveals alterations in donkey milk lipids according to lactation

M Li, W Li, J Wu, Y Zheng, J Shao, Q Li, S Kang… - Food Chemistry, 2020 - Elsevier
The composition of donkey milk is similar to that of human milk. However, the lipid content in
donkey milk is lower than that in human milk. Thus far, the lipid composition of donkey milk …

Roles of specific lipid species in the cell and their molecular mechanism

T Kimura, W Jennings, RM Epand - Progress in lipid research, 2016 - Elsevier
Thousands of different molecular species of lipids are present within a single cell, being
involved in modulating the basic processes of life. The vast number of different lipid species …

Analysis of lipidomics profile of rice and changes during storage by UPLC-Q-extractive orbitrap mass spectrometry

D Zhang, X Duan, B Shang, Y Hong, H Sun - Food Research International, 2021 - Elsevier
Rice is one of major staple food worldwide; however, lipid profile of rice and changes during
storage remain unclear. Herein, an UPLC-Q-Exactive Orbitrap/MS method was applied for …

Cardiac mitochondrial energy metabolism in heart failure: Role of cardiolipin and sirtuins

VW Dolinsky, LK Cole, GC Sparagna… - Biochimica et Biophysica …, 2016 - Elsevier
Mitochondrial oxidation of fatty acids accounts for the majority of cardiac ATP production in
the heart. Fatty acid utilization by cardiac mitochondria is controlled at the level of fatty acid …

[HTML][HTML] Lipidomic profiles of the heart and circulation in response to exercise versus cardiac pathology: a resource of potential biomarkers and drug targets

YK Tham, BC Bernardo, K Huynh, JYY Ooi, XM Gao… - Cell reports, 2018 - cell.com
Exercise-induced heart growth provides protection against cardiovascular disease, whereas
disease-induced heart growth leads to heart failure. These distinct forms of growth are …

The critical roles of STING in mitochondrial homeostasis

S Zou, B Wang, K Yi, D Su, Y Chen, N Li… - Biochemical …, 2024 - Elsevier
The stimulator of interferon genes (STING) is a crucial signaling hub in the immune system's
antiviral and antimicrobial defense by detecting exogenous and endogenous DNA. The …

Sex-specific cardiac cardiolipin remodelling after doxorubicin treatment

M Moulin, A Solgadi, V Veksler, A Garnier… - Biology of sex …, 2015 - Springer
Background Imbalance in lipid metabolism and membrane lipid homeostasis has been
observed in numerous diseases including heart failure and cardiotoxicity. Growing evidence …

The cardiac lipidome in models of cardiovascular disease

MM Tomczyk, VW Dolinsky - Metabolites, 2020 - mdpi.com
Cardiovascular disease (CVD) is the leading cause of death worldwide. There are
numerous factors involved in the development of CVD. Among these, lipids have an …