Oncolytic virus (OV) therapy is an emerging anti-cancer approach that utilizes viruses to
preferentially infect and kill cancer cells, while not harming healthy cells. Vesicular stomatitis …

The heterogeneous nuclear ribonucleoproteins (hnRNPs) are a diverse family of RNA
binding proteins that are implicated in RNA metabolism, such as alternative splicing, mRNA …

LINE1s occupy 17% of the human genome and are its only active autonomous mobile DNA.
L1s are also responsible for genomic insertion of processed pseudogenes and> 1 million …

Vesicular stomatitis virus (VSV) is a prototypic nonsegmented negative-strand RNA virus.
VSV's broad cell tropism makes it a popular model virus for many basic research …

In a genome-wide small interfering RNA (siRNA) screen, we recently identified the interferon
(IFN)-inducible protein 35 (IFI35; also known as IFP35) as a factor required for vesicular …

Negative-strand (NS) RNA viruses comprise many pathogens that cause serious diseases in
humans and animals. Despite their clinical importance, little is known about the host factors …

Porcine epidemic diarrhea virus (PEDV) replicates in the cytoplasm of infected cells, but its
nucleocapsid (N) protein localizes specifically to the nucleolus. The mechanism of nuclear …

Previous studies from our laboratory revealed that cellular poly (C) binding protein 2
(PCBP2) downregulates vesicular stomatitis virus (VSV) gene expression. We show here …

Porcine reproductive and respiratory syndrome virus (PRRSV) infection of swine results in
substantial economic losses to the swine industry worldwide. Identification of cellular factors …

The capsid (C) protein of the Flaviviridae family members is involved in nucleocapsid
formation and virion assembly. However, the influence of C protein-interacting partners on …