Ultrasmall gold nanoclusters (Au NCs), with a particle size of∼ 1 nm, have recently emerged
as a promising class of nanoparticles, due to their well-defined molecular formulae and …

Growing developments in engineered nanomaterials (NMs) and their wide applications
inevitably raise environmental and human health concerns. Upon contact with biological …

The extracellular matrix protects biofilm cells by reducing diffusion of antimicrobials.
Tobramycin is an antibiotic used extensively to treat P. aeruginosa biofilms, but it is …

The use of nanoparticles (NPs) in biomedicine has made a gradual transition from proof-of-
concept to clinical applications, with several NP types meeting regulatory approval or …

Ultrasmall gold nanoparticles (usNPs) and nanoclusters are an emerging class of
nanomaterials exhibiting distinctive physicochemical properties and in vivo behaviors …

To date, much effort has been devoted toward the study of protein corona formation onto
large gold nanoparticles (GNPs). However, the protein corona concept breaks down for …

Nanoparticles (NPs) provide multipurpose platforms for a wide range of biological
applications. These applications are enabled through molecular design of surface …

We describe a process for engineering a synthetic polymer nanoparticle (NP) that functions
as an effective, broad-spectrum metalloproteinase inhibitor. Inhibition is achieved by …

Multivalent aptamers that interact with their target proteins through multiple sites exhibit
much stronger binding strengths than their monovalent counterparts. In this work, we have …

Monoamine oxidase inhibitors (MAOIs) are a class of drugs that can be used in the treatment
of Parkinson's disease, clinical depression, and anxiety by targeting monoamine oxidase B …