Epitope-based vaccine design: a comprehensive overview of bioinformatics approaches
Highlights•Epitope vaccines provide maximal therapeutic efficacy with minimal side
effects.•Reverse vaccinology can be used for designing epitope vaccines.•Computational …
effects.•Reverse vaccinology can be used for designing epitope vaccines.•Computational …
An overview of in silico vaccine design against different pathogens and cancer
K Kardani, A Bolhassani, A Namvar - Expert Review of Vaccines, 2020 - Taylor & Francis
Introduction Due to overcome the hardness of the vaccine design, computational
vaccinology is emerging widely. Prediction of T cell and B cell epitopes, antigen processing …
vaccinology is emerging widely. Prediction of T cell and B cell epitopes, antigen processing …
THPdb: Database of FDA-approved peptide and protein therapeutics
THPdb (http://crdd. osdd. net/raghava/thpdb/) is a manually curated repository of Food and
Drug Administration (FDA) approved therapeutic peptides and proteins. The information in …
Drug Administration (FDA) approved therapeutic peptides and proteins. The information in …
Design of a multiepitope‐based peptide vaccine against the e protein of human COVID‐19: an immunoinformatics approach
MI Abdelmageed, AH Abdelmoneim… - BioMed research …, 2020 - Wiley Online Library
Background. A new endemic disease has spread across Wuhan City, China, in December
2019. Within few weeks, the World Health Organization (WHO) announced a novel …
2019. Within few weeks, the World Health Organization (WHO) announced a novel …
mAHTPred: a sequence-based meta-predictor for improving the prediction of anti-hypertensive peptides using effective feature representation
Motivation Cardiovascular disease is the primary cause of death globally accounting for
approximately 17.7 million deaths per year. One of the stakes linked with cardiovascular …
approximately 17.7 million deaths per year. One of the stakes linked with cardiovascular …
Identification of vaccine targets in pathogens and design of a vaccine using computational approaches
Antigen identification is an important step in the vaccine development process.
Computational approaches including deep learning systems can play an important role in …
Computational approaches including deep learning systems can play an important role in …
Computer-aided designing of immunosuppressive peptides based on IL-10 inducing potential
In the past, numerous methods have been developed to predict MHC class II binders or T-
helper epitopes for designing the epitope-based vaccines against pathogens. In contrast …
helper epitopes for designing the epitope-based vaccines against pathogens. In contrast …
Computer-aided prediction and design of IL-6 inducing peptides: IL-6 plays a crucial role in COVID-19
Abstract Interleukin 6 (IL-6) is a pro-inflammatory cytokine that stimulates acute phase
responses, hematopoiesis and specific immune reactions. Recently, it was found that the IL …
responses, hematopoiesis and specific immune reactions. Recently, it was found that the IL …
PEPlife: a repository of the half-life of peptides
Short half-life is one of the key challenges in the field of therapeutic peptides. Various
studies have reported enhancement in the stability of peptides using methods like chemical …
studies have reported enhancement in the stability of peptides using methods like chemical …
Designing of a Recombinant Multi-Epitopes Based Vaccine against Enterococcus mundtii Using Bioinformatics and Immunoinformatics Approaches
M Alharbi, A Alshammari, AF Alasmari… - International journal of …, 2022 - mdpi.com
Enterococcus species are an emerging group of bacterial pathogens that have a significant
role in hospital-associated infections and are associated with higher mortality and morbidity …
role in hospital-associated infections and are associated with higher mortality and morbidity …