Diabetic cardiomyopathy: mechanisms and new treatment strategies targeting antioxidant signaling pathways

K Huynh, BC Bernardo, JR McMullen… - Pharmacology & …, 2014 - Elsevier
Cardiovascular disease is the primary cause of morbidity and mortality among the diabetic
population. Both experimental and clinical evidence suggest that diabetic subjects are …

The renin angiotensin aldosterone system in obesity and hypertension: roles in the cardiorenal metabolic syndrome

PK Cabandugama, MJ Gardner… - Medical Clinics, 2017 - medical.theclinics.com
The seminal role of hypertension in the pathogenesis of the cardiorenal metabolic syndrome
(CRS) has significantly evolved over the past 5 years. The physiology of this is rooted in the …

[HTML][HTML] Blood pressure lowering and risk of new-onset type 2 diabetes: an individual participant data meta-analysis

M Nazarzadeh, Z Bidel, D Canoy, E Copland, M Wamil… - The Lancet, 2021 - thelancet.com
Background Blood pressure lowering is an established strategy for preventing microvascular
and macrovascular complications of diabetes, but its role in the prevention of diabetes itself …

Incident diabetes in clinical trials of antihypertensive drugs: a network meta-analysis

WJ Elliott, PM Meyer - The Lancet, 2007 - thelancet.com
Background The effect of different classes of antihypertensive drugs on incident diabetes
mellitus is controversial because traditional meta-analyses are hindered by heterogeneity …

Renin-angiotensin system and cardiovascular risk

RE Schmieder, KF Hilgers, MP Schlaich, BMW Schmidt - The Lancet, 2007 - thelancet.com
The renin-angiotensin system is a major regulatory system of cardiovascular and renal
function. Basic research has revealed exciting new aspects, which could lead to novel or …

Renin–angiotensin system, natriuretic peptides, obesity, metabolic syndrome, and hypertension: an integrated view in humans

R Sarzani, F Salvi, P Dessì-Fulgheri… - Journal of …, 2008 - journals.lww.com
The obesity pandemic is closely related to hypertension and metabolic syndrome. Visceral
adipose tissue plays a key role in the metabolic and cardiovascular complications of being …

Guías latinoamericanas de hipertensión arterial

RA Sánchez, M Ayala, H Baglivo… - Revista chilena de …, 2010 - SciELO Chile
Guías Latinoamericanas de Hipertensión Arterial SciELO - Scientific Electronic Library Online
vol.29 número1 Infarto perioperatorio en cirugía no-cardíaca y dexmedetomidina Cierre …

Screening for type 2 diabetes: literature review and economic modelling

N Waugh, G Scotland, P McNamee, M Gillett… - HEALTH …, 2007 - emerald.com
Background The National Screening Committee (NSC) is responsible for providing advice
on screening policy to all parts of the UK. A review of policy on screening for type 2 diabetes …

Angiotensin receptor blockers may increase risk of myocardial infarction: unraveling the ARB-MI paradox

MH Strauss, AS Hall - Circulation, 2006 - Am Heart Assoc
838 medication have significant differences with regard to their ancillary pharmacological
properties and thereby also their profile at a molecular/cellular level. Furthermore, these …

The renin angiotensin system and the metabolic syndrome

AD de Kloet, EG Krause, SC Woods - Physiology & behavior, 2010 - Elsevier
The renin angiotensin system (RAS; most well-known for its critical roles in the regulation of
cardiovascular function and hydromineral balance) has regained the spotlight for its …