Alterations of neural activity in the prefrontal cortex associated with deficits in working memory performance

S Li, MC Rosen, S Chang, S David… - Frontiers in Behavioral …, 2023 - frontiersin.org
Working memory (WM), a core cognitive function, enables the temporary holding and
manipulation of information in mind to support ongoing behavior. Neurophysiological …

Dynamical latent state computation in the male macaque posterior parietal cortex

KJ Lakshminarasimhan, E Avila, X Pitkow… - Nature …, 2023 - nature.com
Success in many real-world tasks depends on our ability to dynamically track hidden states
of the world. We hypothesized that neural populations estimate these states by processing …

Working memory expedites the processing of visual signals within the extrastriate cortex

M Roshanaei, Z Bahmani, K Clark, MR Daliri… - Iscience, 2024 - cell.com
Working memory is the ability to maintain information in the absence of sensory input. In this
study, we investigated how working memory benefits processing in visual areas. Using a …

More prominent nonlinear mixed selectivity in the dorsolateral prefrontal than posterior parietal cortex

W Dang, S Li, S Pu, XL Qi, C Constantinidis - Eneuro, 2022 - eneuro.org
Neurons in the dorsolateral prefrontal cortex (dlPFC) and posterior parietal cortex (PPC) are
activated by different cognitive tasks and respond differently to the same stimuli depending …

Single-neuron and population measures of neuronal activity in working memory tasks

R Mozumder, C Constantinidis - Journal of …, 2023 - journals.physiology.org
Information represented in working memory is reflected in the firing rate of neurons in the
prefrontal cortex and brain areas connected to it. In recent years, there has been an …

Contributions of narrow-and broad-spiking prefrontal and parietal neurons on working memory tasks

R Mozumder, S Chung, S Li… - Frontiers in Systems …, 2024 - frontiersin.org
Neurons that generate persistent activity in the primate dorsolateral prefrontal and posterior
parietal cortex have been shown to be predictive of behavior in working memory tasks …

Dynamical latent state computation in the posterior parietal cortex

KJ Lakshminarasimhan, E Avila, X Pitkow, DE Angelaki - bioRxiv, 2022 - biorxiv.org
Success in many real-world tasks depends on our ability to dynamically track hidden states
of the world. To understand the underlying neural computations, we recorded brain activity …

Influence of Fast-Spiking Prefrontal Neurons on Working Memory Behavior

S Chung, R Mozumder, S Li, C Constantinidis - bioRxiv, 2023 - biorxiv.org
Working memory is a limited-capacity system for maintaining and manipulating information
for recall. Neurons that generate persistent activity in the primate dorsolateral prefrontal and …

Effects of ketamine on frontoparietal interactions during working memory in macaque monkeys

L Ma, N Katyare, K Johnston, S Everling - bioRxiv, 2023 - biorxiv.org
Schizophrenia is known as a syndrome of dysconnection among brain regions. As a model
for this syndrome, low doses of N-methyl-D-aspartate (NMDA) receptor antagonists, such as …

Machine Learning Models for Analyzing Working Memory Data

JA Gerstenberger - 2024 - search.proquest.com
In primate neurophysiology, it is consistently observed that during working memory tasks,
neural tuning manifests as heightened firing rates, persisting throughout the delay period of …