[HTML][HTML] Traumatic spinal cord injury
Traumatic spinal cord injury (SCI) has devastating consequences for the physical, social and
vocational well-being of patients. The demographic of SCIs is shifting such that an …
vocational well-being of patients. The demographic of SCIs is shifting such that an …
[HTML][HTML] Glial cells shape pathology and repair after spinal cord injury
Glial cell types were classified less than 100 years ago by del Rio-Hortega. For instance, he
correctly surmised that microglia in pathologic central nervous system (CNS) were …
correctly surmised that microglia in pathologic central nervous system (CNS) were …
[HTML][HTML] Minocycline as treatment for psychiatric and neurological conditions: a systematic review and meta-analysis
Minocycline has anti-inflammatory, antioxidant, and anti-apoptotic properties that explain the
renewed interest in its use as an adjunctive treatment for psychiatric and neurological …
renewed interest in its use as an adjunctive treatment for psychiatric and neurological …
Hydrogels in spinal cord injury repair strategies
Nowadays there are at present no efficient therapies for spinal cord injury (SCI), and new
approaches have to be proposed. Recently, a new regenerative medicine strategy has been …
approaches have to be proposed. Recently, a new regenerative medicine strategy has been …
Limiting multiple sclerosis related axonopathy by blocking Nogo receptor and CRMP-2 phosphorylation
S Petratos, E Ozturk, MF Azari, R Kenny, J Young Lee… - Brain, 2012 - academic.oup.com
Multiple sclerosis involves demyelination and axonal degeneration of the central nervous
system. The molecular mechanisms of axonal degeneration are relatively unexplored in …
system. The molecular mechanisms of axonal degeneration are relatively unexplored in …
[HTML][HTML] Cellular treatments for spinal cord injury: the time is right for clinical trials
MG Fehlings, R Vawda - Neurotherapeutics, 2011 - Elsevier
More than 1 million people in the United States live with a spinal cord injury (SCI). Despite
medical advances, many patients with SCIs still experience substantial neurological …
medical advances, many patients with SCIs still experience substantial neurological …
Nanomedicine innovations in spinal cord injury management: Bridging the gap
M Rahmanian, A Ghahremani, P Kesharwani… - Environmental …, 2023 - Elsevier
Spinal cord injury (SCI) has devastating effects on a person's physical, social, and
professional well-being. It is a life-altering neurological condition that significantly impacts …
professional well-being. It is a life-altering neurological condition that significantly impacts …
Introduction to the guidelines for the management of acute cervical spine and spinal cord injuries
MN Hadley, BC Walters - Neurosurgery, 2013 - journals.lww.com
Medical evidence-based guidelines, when properly produced, represent a contemporary
scientific summary of accepted management, imaging, assessment, classification, and …
scientific summary of accepted management, imaging, assessment, classification, and …
Polymeric nanoparticle system to target activated microglia/macrophages in spinal cord injury
S Papa, R Ferrari, M De Paola, F Rossi… - Journal of controlled …, 2014 - Elsevier
The possibility to control the fate of the cells responsible for secondary mechanisms
following spinal cord injury (SCI) is one of the most relevant challenges to reduce the post …
following spinal cord injury (SCI) is one of the most relevant challenges to reduce the post …
Deep brain stimulation of the midbrain locomotor region improves paretic hindlimb function after spinal cord injury in rats
LC Bachmann, A Matis, NT Lindau, P Felder… - Science translational …, 2013 - science.org
In severe spinal cord injuries, the tracts conveying motor commands to the spinal cord are
disrupted, resulting in paralysis, but many patients still have small numbers of spared fibers …
disrupted, resulting in paralysis, but many patients still have small numbers of spared fibers …