Background Partial artemisinin resistance is suspected if delayed parasite clearance (ie,
persistence of parasitaemia on day 3 after treatment initiation) is observed. Validated …

Following a decade-long scale up of malaria control through vector control interventions, the
introduction of rapid diagnostic tests and highly efficacious Artemisinin-based Combination …

Introduction: Plasmodium falciparum, the deadly agent of malaria, is notorious for its
capacity to develop drug resistance. Treatment failures of artemisinin therapy regimens …

Abstract Background. Rapid diagnostic tests (RDTs) account for more than two-thirds of
malaria diagnoses in Africa. Deletions of the Plasmodium falciparum hrp2 (pfhrp2) gene …

BACkground Plasmodium resistance to antimalarial medicines is one of the major obstacles
in the fight against malaria. Comprehensive, up-to-date understanding of the scope of …

The rapid and aggressive spread of artemisinin-resistant Plasmodium falciparum carrying
the C580Y mutation in the kelch13 gene is a growing threat to malaria elimination in …

Drug resistance has emerged as one of the greatest challenges facing malaria control. The
recent emergence of resistance to artemisinin (ART) and its partner drugs in ART-based …

Artemisinin-based combination therapies (ACTs) have been vital in reducing malaria
mortality rates since the 2000s. Their efficacy, however, is threatened by the emergence and …

Abstract Background. In 2005, Ghana adopted artemisinin-based combination therapy
(ACT) for primary treatment of falciparum malaria. A comprehensive study of the drug …

Molecular markers for surveillance of Plasmodium falciparum resistance to current
antimalarials are sorely needed. A 28-day efficacy study of artemether-lumefantrine in …