Since their original discovery as regulators of follicle-stimulating hormone (FSH) secretion
and erythropoiesis, the TGF-β family members activin and inhibin have been shown to …

Members of the TGF-β superfamily regulate many aspects of development, including
adipogenesis. Studies in cells and animal models have characterized the effects of …

After the initial discovery of activins as important regulators of reproduction, novel and
diverse roles have been unraveled for them. Activins are expressed in various tissues and …

Activin ligands are formed from two disulfide-linked inhibin β (Inhβ) subunit chains. They
exist as homodimeric proteins, as in the case of activin A (ActA; InhβA/InhβA) or activin C …

Body-fat distribution is a risk factor for adverse cardiovascular health consequences. We
analyzed the association of body-fat distribution, assessed by waist-to-hip ratio adjusted for …

Brown adipocyte activation or beige adipocyte emergence in white adipose tissue (WAT)
increases energy expenditure, leading to a reduction in body fat mass and improved …

Objective The liver is a central regulator of energy metabolism exerting its influence both
through intrinsic processing of substrates such as glucose and fatty acid as well as by …

We previously identified a quantitative trait locus for adiposity, non-insulin-dependent
diabetes 5 (Nidd5), on mouse chromosome 2. In the current study, we identified the actual …

Oxidative stress‐induced reactive oxygen species, DNA damage, apoptosis, and cellular
senescence have been associated with reduced osteoprogenitors in a reciprocal fashion to …

Human adipose tissue is a major site of expression of inhibin beta B (INHBB) which
homodimerizes to form the novel adipokine activin B. Our aim was to determine if molecules …